Results 41 to 50 of about 835,042 (245)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Effects of Decreasing Foot Strike Angle on Lower Extremity Shock Attenuation Measured with Wearable Sensors

Sensors
Shock attenuation may be a clinically feasible method to assess changes in lower extremity joint loading induced by gait modifications, such as decreasing foot strike angle (forefoot striking).
Lucas Sarantos, David J. Zeppetelli, Cole A. Dempsey, Takashi Nagai, Caleb D. Johnson   +4 more
doaj   +1 more source

Parecoxib Reduces Systemic Inflammation and Acute Lung Injury in Burned Animals with Delayed Fluid Resuscitation

International Journal of Inflammation, 2014
Burn injuries result in the release of proinflammatory mediators causing both local and systemic inflammation. Multiple organ dysfunctions secondary to systemic inflammation after severe burn contribute to adverse outcome, with the lungs being the first ...
Si Jack Chong, Yong Chiat Wong, Jian Wu, Mui Hong Tan, Jia Lu, Shabbir M. Moochhala   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Time to First Injury After Knee Surgery in U.S. Army Soldiers: A Survival Analysis

Sports Medicine - Open
Background Knee injuries, including those requiring surgical intervention, are a leading cause of disability in U.S. Army soldiers. Previous studies investigating the risk of injury after surgery have primarily focused on civilian populations and lack ...
Benjamin G. Adams, Richard B. Westrick, Perman Gochyyev, Kathryn M. Taylor   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Association between salivary and blood hormone concentrations using an automated electrochemiluminescence immunoassay technique: Challenges and pitfalls

Experimental Physiology
Blood‐based measures are considered the gold standard for evaluating steroid hormone concentrations, particularly for confirmation of hormone profiles in female‐specific research.
Natalie J. Hardaker, Patria A. Hume, Stacy T. Sims, Tom Stewart, Doug A. King   +4 more
doaj   +1 more source

The Relations among Environmental Performance, Environmental and Firm Performance

The Indonesian Journal of Accounting Research, 2017
Abstract : Companies tend to disclose good news . If the company has good environmental performance , it will be disclosed in the financial statements . This disclosure of environmental information will enhance the reputation of the company ; thus it will increase company performance .
openaire   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source