Results 111 to 120 of about 1,406,006 (303)

Is a Voluntary Approach an Effective Environmental Policy Instrument? A Case for Environmental Management Systems [PDF]

Using Japanese facility-level data from an Organisation for Economic Co-operation and Development survey, we estimate the effects of implementation of ISO14001 and publication of environmental reports on the facilities’ environmental performance.
Arimura, Toshi, Hibiki, Akira, Katayama, Hajime   +2 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Proposal of an environmental performance index to assess leather-manufacturing companies

Green Technologies and Sustainability
Despite the global economic and environmental importance of the leather industry, the specialized literature still presents an important gap in analyzing the environmental performance of the leather manufacturing process from the waste generated.
Marcelo Girotto Rebelato, Andréia Marize Rodrigues, Bruna Sousa Ferreira   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Çevresel performans endeksi kapsamında Türkiye’de sürdürülebilir kalkınma: Çevresel ve kentsel göstergeler ışığında bir değerlendirme

Afyon Kocatepe Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi
Bu çalışmanın amacı Yale Üniversitesi tarafından yayımlanan Çevresel Performans Endeksi (EPI) kapsamında Türkiye’nin çevresel ve kentsel göstergeler bağlamında sürdürülebilir kalkınma düzeyinin değerlendirilmesidir.
Sadegül Durgun, Yeter Avşar
doaj  

Yields and qualities of pigeonpea varieties grown under smallholder farmers’ conditions in Eastern and Southern Africa [PDF]

, 2007
Pigeonpea is one of the few crops with a high potential for resource-poor farmers due to its complementary resource use when intercropped with maize.
Adu-Gyamfi, J.J., Høgh-Jensen, H, Kamalongo, D., Myaka, F.A., Ngwira, A., Odgaard, R., Sakala, W.D., Vesterager, J.M.   +7 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Measuring human and Sustainable Development: An Integrated Approach for European Countries [PDF]

During the last few years, sustainable development has represented one of the most important policy goals at global level and how to design specific policy actions, measuring performance and results continues to present a challenge.
Salvatore Monni, Valeria Costantini
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

KETERKAITAN KINERJA LINGKUNGAN, PENGUNGKAPAN CORPORATE SOCIAL RESPONSIBILITY (CSR) DAN KINERJA FINANSIAL [PDF]

, 2012
The purpose of this study was to determine the linkages between environmental performance, CSR Disclosure, and financial performance of the company.
FITRIYANI, Fitriyani, SITI , Mutmainah
core