Results 161 to 170 of about 331,456 (298)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Individual Differences in the "Cognitive-Adaptive Gap" Among Children with Autism Spectrum Disorder: A Latent Profile Analysis of the Moderating Role of Family Environment. [PDF]

J Intell
Shao N, Wu L, Li W, Song C, Jin W, Hu L, Zhang X, Zhu Z.   +7 more
europepmc   +1 more source

Technical and Environmental efficiencies and Best Management Practices in Agriculture

An input distance function (IDF) is estimated to empirically evaluate and analyze the technical and environmental efficiencies of 210 farms located in the Chaudière watershed (Quebec), where water quality problems are particularly acute because of the ...
Tamini, Lota D., Larue, Bruno
core  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Environmental Performance Index of Financial products

Abstracts for ILCAJ meeting, 2009
Honda, Tomonori, Inaba, Atsushi
openaire   +1 more source

Hybrid Supervised-Unsupervised Modeling for Post-Hurricane Private Well Contamination Risk Score Using Empirical Validation and Community-Informed Assessment. [PDF]

Geohealth
Lin J, Zhang J, Wei E, Shea K, Wang HJ, Apanasovich TV, Liddie JM, Hernandez E, Norford C, Hu XC.   +9 more
europepmc   +1 more source

An investigation into the legal performance of small and mediumsized enterprises (SMEs), encompassing compliance levels, the impact and effectiveness of environmental legislation and improving SME environmental compliance control systems

, 2011
There has been a great deal written about the difficulties faced by small and medium-sized enterprises (SMEs) compared to larger businesses. SMEs face difficulties complying with environmental legislation, particularly because of the amount of complex ...
Wilson, Christopher D.H.
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Monitoring and Early Warning of the Cage-Rearing Broiler Farming Environment Based on an Inspection Robot. [PDF]

Animals (Basel)
Luo S, Kong X, Xie X, Zhang W, Zheng P, Zhu H, Hao D, Sun J, Chen C.   +8 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source