Results 141 to 150 of about 15,839,879 (256)

Disrupted Brain Structure and Function in Alzheimer's Disease Patients With Behavioral and Psychological Symptoms

open access: yesiNew Medicine, EarlyView.
ABSTRACT Objective Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in Alzheimer’s disease (AD), but the underlying mechanisms are unclear. This study aims to elucidate the neuropathological mechanisms underlying BPSD by investigating gray matter volume (GMV) and brain connectivity in AD patients with and without BPSD ...
Xuerui Pang   +8 more
wiley   +1 more source

Environmental sustainability and financial performance of SMEs [PDF]

open access: yes
This paper focuses on the relationship between environmental sustainability and the financial performance of SMEs in terms of profit development and revenue development. The analysis uses a unique dataset of 337 Dutch and Chinese firms.
Nasser Bouman   +2 more
core  

Engineered 3D cultured human nasal mucosa mesenchymal stem cell derived sEVs for targeted brain‐derived neurotrophic factor delivery to enhance neurogenesis and attenuate brain damage

open access: yesInterdisciplinary Medicine, EarlyView.
This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang   +13 more
wiley   +1 more source

Construction and Application of a Novel C‐Vine Copula‐Based Multi‐Variate Ecological Drought Index

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT A comprehensive ecological drought index capturing vegetation growth conditions and meteorological–hydrological variability is essential for assessing ecological drought and optimizing water resource management. This study selected soil moisture (SM), actual evapotranspiration (ET), land surface temperature (LST) and leaf area index (LAI) to ...
Haofei Zhang, Xingye Han, Zhijun Wu
wiley   +1 more source

The role of rare copy number variants in early‐onset depression

open access: yesJCPP Advances, EarlyView.
Abstract Background Depression is a highly heterogeneous condition. Depression with an onset in childhood and early adolescence has a worse clinical course, is more heritable, and shows a lower genetic correlation with other depression subtypes, than does later‐onset depression.
Charlotte A. Dennison   +12 more
wiley   +1 more source

Desempenho ambiental é democrático? Uma análise comparada do Democracy Index e Environment Performance Index (EPI)

open access: yes
The objective of this study was to conduct an in-depth analysis of the importance of the environment in democracies, aiming to understand whether democratic countries tend to show a greater commitment to environmental preservation compared to non ...
Wohlenberg Pires, Cássio Alex   +1 more
core   +1 more source

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