Results 121 to 130 of about 7,058,672 (250)
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Guiding land acquisition and protection in Connecticut, 2007-2012
Title from cover.; "September 2007."; Originally published: The Connecticut green plan. [Hartford] : Connecticut Dept.
core +1 more source
Updated irregularly; Began in 2011.; Title from home page (publisher's Web site, viewed July 5, 2011).; At head of title: State of Connecticut.; Harvested from the web on 5/26/17Official website of the Connecticut Dept.
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MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Updated irregularly; Began in 2011.; Title from home page (publisher's Web site, viewed July 5, 2011).; At head of title: State of Connecticut.; Harvested from the web on 8/10/12Official website of the Connecticut Dept.
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Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Updated irregularly; Began in 2011.; Title from home page (publisher's Web site, viewed July 5, 2011).; At head of title: State of Connecticut.; Harvested from the web on 10/3/15Official website of the Connecticut Dept.
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TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Trade Cooperation, Environmental Protection, and Sustainability: The Belt and Road Initiative Perspective. [PDF]
Zhang YF +4 more
europepmc +1 more source
This document presents the Environmental Protection Agency's nutrient criteria for Lakes and Reservoirs in Nutrient Ecoregion ...
United States Environmental Protection Agency; Office of Water
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