Results 31 to 40 of about 830,984 (300)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The National Tenth Five-Year Plan for Environmental Protection(Abstract) [PDF]
The State Council approved the National Tenth Five-Year Plan for Environmental Protection on 26 December 2001, requesting that loca1 governments and the various departments strengthen environmental protection in close relation with the economic ...
State Environmental Protection Administration
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Biofilms and Environmental Protection
Biofilms are the result of adhesion and growth of microorganisms at interfaces. They consist mainly of water (70-95 % wet weight), held by the highly hydrated extracellular polymers (EPS, 70-95 % dry weight) in which the microorganisms are embedded.
openaire +2 more sources
Environmental Protection Implementation Plan [PDF]
This Environmental Protection Implementation Plan is intended to ensure that the environmental program objectives of Department of Energy Order 5400.1 are achieved at SNL/California. This document states SNL/California`s commitment to conduct its operations in an environmentally safe and responsible manner.
openaire +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Control of mushroom sciarid fly Lycoriella inguena (Dufour) with an azadirachtin-based insecticide [PDF]
The impact of a bioinsecticide based on azadirachtin (Ozoneem trishul 1 %) on the abundance of mushroom flies (Sciaridae: Diptera) was compared to the effect of a commercial formulation of the malathion-based chemical insecticide Etiol tečni. Experiments
Drobnjaković Tanja +6 more
doaj
Antimicrobial activity of biochemical substances against pathogens of cultivated mushrooms in Serbia [PDF]
Disease control with few or no chemicals is a major challenge for mushroom growers in the 21st century. An alarming incidence of resistance to antibiotics in bacteria, and to fungicides among mycopathogenic fungi requires effective alternatives. Previous
Potočnik Ivana +5 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

