Results 31 to 40 of about 830,984 (300)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The National Tenth Five-Year Plan for Environmental Protection(Abstract) [PDF]

open access: yes, 2001
The State Council approved the National Tenth Five-Year Plan for Environmental Protection on 26 December 2001, requesting that loca1 governments and the various departments strengthen environmental protection in close relation with the economic ...
State Environmental Protection Administration
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Biofilms and Environmental Protection

open access: yesWater Science and Technology, 1993
Biofilms are the result of adhesion and growth of microorganisms at interfaces. They consist mainly of water (70-95 % wet weight), held by the highly hydrated extracellular polymers (EPS, 70-95 % dry weight) in which the microorganisms are embedded.
openaire   +2 more sources

Environmental Protection Implementation Plan [PDF]

open access: yes, 1998
This Environmental Protection Implementation Plan is intended to ensure that the environmental program objectives of Department of Energy Order 5400.1 are achieved at SNL/California. This document states SNL/California`s commitment to conduct its operations in an environmentally safe and responsible manner.
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Control of mushroom sciarid fly Lycoriella inguena (Dufour) with an azadirachtin-based insecticide [PDF]

open access: yesPesticidi i Fitomedicina, 2019
The impact of a bioinsecticide based on azadirachtin (Ozoneem trishul 1 %) on the abundance of mushroom flies (Sciaridae: Diptera) was compared to the effect of a commercial formulation of the malathion-based chemical insecticide Etiol tečni. Experiments
Drobnjaković Tanja   +6 more
doaj  

Antimicrobial activity of biochemical substances against pathogens of cultivated mushrooms in Serbia [PDF]

open access: yesPesticidi i Fitomedicina, 2016
Disease control with few or no chemicals is a major challenge for mushroom growers in the 21st century. An alarming incidence of resistance to antibiotics in bacteria, and to fungicides among mycopathogenic fungi requires effective alternatives. Previous
Potočnik Ivana   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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