Results 41 to 50 of about 7,058,672 (250)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Artificial Intelligence-Based Tools for Process Optimization: Case Study—Bromocresol Green Decolorization with Active Carbon

Adsorption Science & Technology, 2022
This study highlights the benefits of optimizing the decolorization of bromocresol green (a colorant/pH indicator widely used in the industry, whose degradation produces toxic byproducts) by adsorption on active carbon.
Gabriel Dan Suditu, Elena Niculina Drăgoi, Alexandra Georgiana Apostică, Andra Maria Mănăilă, Veronica Mădălina Radu, Adrian Cătălin Puițel, Mircea Teodor Nechita   +6 more
doaj   +1 more source

Office of Adjudications; Public notices

, 2008
Updated irregularly; Began in 2002?; Title from home page updated to 2007 (viewed Apr. 15, 2008).; Harvested from the web on 4/17/08Proposed decisions issued by the Office of Adjudications-- Scoping notices published in the Environmental monitor-- Final ...
Connecticut. Dept. of Environmental Protection.
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Office of Adjudications; Public notices

, 2007
Updated irregularly; Began in 2002?; Title from home page updated to 2007 (viewed Apr. 15, 2008).; Harvested from the web on 7/19/07Proposed decisions issued by the Office of Adjudications-- Scoping notices published in the Environmental monitor-- Final ...
Connecticut. Dept. of Environmental Protection.
core   +1 more source

Carcinogenicity of vinyl acetate: evidence from multiple data streams

Environmental Health
Background Vinyl acetate (VA) is a synthetic chemical that can be metabolized to form the carcinogen acetaldehyde (AA). This paper summarizes the key evidence relevant to the evaluation of VA’s carcinogenicity.
Kate Li, Karin Ricker, Feng C Tsai, Vanessa Cheng, Gwendolyn Osborne, Neela Guha, Sarah Elmore, Isabel Alvarado-Cruz, Martha S Sandy, Meng Sun   +9 more
doaj   +1 more source

Control of pepper bacterial spot and tomato bacterial speck using bactericides in combination with a plant activator [PDF]

Pesticidi i Fitomedicina, 2019
The efficacy of a formulated product of tea tree oil (TTO) and a standard copper based bactericide in combinations with acibenzolar-S-methyl (ASM) for control of bacterial spot of pepper and bacterial speck of tomato was evaluated under controlled ...
Rekanović Emil, Potočnik Ivana, Stepanović Miloš, Todorović Biljana, Mihajlović Milica, Milijašević-Marčić Svetlana   +5 more
doaj  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source