Results 51 to 60 of about 4,952,647 (297)
Planning Theory and Environmental Ethics: Towards the Integration of Biodiversity and Urban Planning
Jurnal Wilayah dan Lingkungan, 2022 Planning is a forward-looking and public-interest process, and for that purpose there is a choice of actions to be taken. Communicative rationality is highly recommended in planning related to the environment.
Fitrawan Umar, Haryo Winarso
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Pour une réhabilitation des seuils en droit de la santé et de l’environnement
Cahiers Droit, Sciences & Technologies, 2014 It has become a commonplace in our time of criticism against scientific rationality to reject thresholds as instruments of public policy in health and environmental fields.
Florence Bellivier, Christine Noiville
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Rational environmental goals and sustainable planning [PDF]
WIT Transactions on Ecology and the Environment, Vol 93, 2006 In Sweden planning towards ecological sustainability starts out from a system of environmental objectives adopted by Parliament in the late 1990s.
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Resources, 2016 Including stakeholder perspectives in environmental decision making is in many countries a legal requirement and is widely seen as beneficial as it can help increase decision legitimacy, likelihood of implementation, and quality of the outcome.
Anna Scolobig, Johan Lilliestam
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Natural environmental impact assessment: A rational approach [PDF]
Environmental Management, 1977 A method is presented which combines environmental indices and estimates of inputs from various land uses to aid in environmental impact assessments. Unweighted pair/group cluster analyses are used to obtain relationships between easily observable environmental indices, such as vegetation types, soils, and geology, based on their mutual recurrence ...
J. L. Gevirts, P. G. Rowe
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