Results 51 to 60 of about 212,973 (309)
, 2011 The self-centeredness of modern organizations leads to environmental destruction and human deprivation. The principle of responsibility developed by Hans Jonas requires caring for the beings affected by our decisions and actions.
Zsolnai, László
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Cognitive biases, heuristics and decision-making in design for behaviour change [PDF]
, 2012 Copyright @ 2012 Social Science Electronic PublishingMuch human behaviour can be seen as decision-making, and so understanding and influencing those decision-making processes could be an important component in design for behaviour change.
Lockton, D
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Revista Direitos Humanos e DemocraciaThe current investigation deals with the scope of the contemporary environmental crisis and its relationship with the neoliberal rationality. In this sense, the issue of such research comes up from the following questions: What is the future prognosis ...
Rodrigo Tonel, Daniel Rubens Cenci
doaj +1 more source
Rational environmental goals and sustainable planning [PDF]
WIT Transactions on Ecology and the Environment, Vol 93, 2006 In Sweden planning towards ecological sustainability starts out from a system of environmental objectives adopted by Parliament in the late 1990s.
openaire +1 more source
Sentience, Rationality, and Moral Status: A Further Reply to Hsiao [PDF]
, 2016 Timothy Hsiao argues that animals lack moral status because they lack the capacity for the sort of higher-level rationality required for membership in the moral community.
Puryear, Stephen
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The Predicament of Nature: Keiko the Whale and The Cultural Politics of Whaling in Iceland [PDF]
, 2006 This cultural analysis reconsiders the modernist narrative about the politics of whales and whale hunting in order to explore Icelandic responses to the return of the killer whale Keiko (star of the Free Willy movies) to Icelandic waters in 1998 ...
Brydon, Anne
core +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source