Results 151 to 160 of about 13,359,027 (313)

Genetic and environmental risk factors of asthma: a narrative review. [PDF]

Front Immunol
Altynova NK, Lebedeva LP, Abdullayeva MS, Kassymbekova AM, Yergali K, Homaira N, Djansugurova LB.   +6 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Autism Spectrum Disorder: Integrating Genetic and Environmental Risk. [PDF]

Cells
Kamijo S, Miwa H, Ikeda K.
europepmc   +1 more source

Mediating Solutions to Environmental Risks [PDF]

Annual Review of Public Health, 1986
S, Gusman, P J, Harter
openaire   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Regional CKD Prevalence and Possible Environmental Risk Factors in Jamaica. [PDF]

Kidney Int Rep
Bikbov B.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Synthesis of Methoxylated Benzoxanthones as Drug Metabolites of Antischistosomal Schistodiones-A Limited Environmental Risk. [PDF]

Molecules
Cesar-Rodo E, Boilevin J, Richard J, Ziniel PD, Belorgey D, Maes L, Angelucci F, Williams DL, Davioud-Charvet E, Lanfranchi DA.   +9 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Editorial: Environmental risk factors and psychosomatic disorders. [PDF]

Front Psychiatry
Yu P, Yu B, Tang W, Yang S.
europepmc   +1 more source