Results 121 to 130 of about 3,370,181 (310)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Organization of Joint Laboratory Studies during Sanitary and Epidemiological Interventions in the Republic of the Congo by Rospotrebnadzor Specialists

Проблемы особо опасных инфекций
The study presents the data on organization of laboratory testing of clinical and environmental samples within the framework of establishing the etiology of the acute intestinal infections outbreak, performed by the specialists of the joint SAET of the ...
S. A. Portenko, E. V. Naidenova, D. A. Agafonov, D. A. Kuznetsova, A. V. Evteev, A. A. Tushinsky, L. N. Dmitrieva, A. D. Katyshev, V. E. Kuklev, N. Obissa, V. Mabiala, J. Loubano, M. Mpompolo, J.-C. Mobousse Misse, S. A. Shcherbakova, V. V. Kutyrev   +15 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

NATURAL BIODEGRADATION OF COPROSTANOL IN AN EXPERIMENTAL SYSTEM OF THREE ENVIRONMENTAL CONDITIONS OF JAKARTA WATERS, INDONESIA [PDF]

, 2004
Constraint of using bio-indicator (coliform bacteria) as an indicator of domestic (sewage) pollution in the environment with high environmental stress encourages the discovering of other alternate indicators.
Bachtiar, Tonny, Radjasa, Ocky Karna, Sabdono, Agus   +2 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A Univariate Optimization Strategy for Pre-concentration of Cobalt(II) in Various Matrixes by a DLLME before Analysis Using FAAS

Indonesian Journal of Chemistry
A procedure based on dispersive liquid-liquid microextraction (DLLME) for cobalt (Co) quantification in an Iraqi environmental matrix by flame atomic absorption spectroscopy (FAAS) was applied in this work.
Zaman Sahb Mehdi, Saher Abdel Reda Ali Alshamkhawy   +1 more
doaj   +1 more source

Isolation of Acanthamoeba isolates belonging to T2, T3, T4 and T7 genotypes from environmental samples in Ankara, Turkey [PDF]

, 2004
Acanthamoeba keratitis is a blinding infection that is becoming increasingly important in human health. Early diagnosis is a prerequisite for successful treatment and requires identification of Acanthamoeba at the genotypic level.
Jayasekera, S., Khan, Naveed Ahmed, Kiliç, A., Sissons, J., Tanyuksel, M.   +4 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Measuring micro-organism gas production [PDF]

, 1973
Transducer, which senses pressure buildup, is easy to assemble and use, and rate of gas produced can be measured automatically and accurately. Method can be used in research, in clinical laboratories, and for environmental pollution studies because of ...
Mills, S. M., Pearson, A. O., Wilkins, J. R.   +2 more
core   +1 more source

First-passage theory of exciton population loss in single-walled carbon nanotubes reveals micron-scale intrinsic diffusion lengths

, 2013
One-dimensional crystals have long range translational invariance which manifests as long exciton diffusion lengths, but such intrinsic properties are often obscured by environmental perturbations.
I. Karatzas, James M. Fraser, Mitchell D. Anderson, P. W. Milonni, Yee-fang Xiao   +4 more
core   +1 more source