Results 91 to 100 of about 1,477,177 (315)

iMESc – an interactive machine learning app for environmental sciences

open access: yesFrontiers in Environmental Science
As environmental sciences increasingly rely on complex datasets, machine learning (ML) has become crucial for identifying patterns and relationships. However, the integration of ML into workflows can pose challenges due to technical barriers or the time ...
Danilo Cândido Vieira   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Protocol for constructing an accessible exposure chamber for in vitro and in vivo modeling of airway environmental exposures

open access: yesSTAR Protocols
Summary: Exposure systems to study the effects of environmental exposures can be costly to purchase and difficult to use. Here, we present an accessible and cost-effective approach to building an exposure chamber in the lab.
Abdo Durra   +11 more
doaj   +1 more source

Swimming and the human microbiome at the intersection of sports, clinical, and environmental sciences: A scoping review of the literature. [PDF]

open access: yesFront Microbiol, 2022
Puce L   +11 more
europepmc   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Increasing collaboration between China and India in the environmental sciences to foster global sustainability. [PDF]

open access: yesAmbio, 2022
Goodale E   +14 more
europepmc   +1 more source

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