Results 91 to 100 of about 11,474,388 (383)

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Arkansas Small-Grain Cultivar Performance Tests 2004-2005 [PDF]

open access: yes, 2005
Small-grain cultivar performance tests are conducted each year in Arkansas by the Arkansas Agricultural Experiment Station, Department of Crop, Soil and Environmental Sciences.
Bacon, R. K.   +2 more
core   +1 more source

Isotopes in hydrology and hydrogeology [PDF]

open access: yes, 2019
The structure, status, and processes of the groundwater system, which can only be acquired through scientific research efforts, are critical aspects of water resource management. Isotope hydrology and hydrogeology is a genuinely interdisciplinary science.
Barbieri, Maurizio
core   +1 more source

Analysis of the influence of environmental parameters on methane flux from floodplains and lakes in the Abobral River, Pantanal, Brazil

open access: yesRevista Ambiente & Água, 2016
This study evaluates the influence of physical and chemical characteristics of the water column in the processes that result in methane emissions in the Pantanal. Two surveys were conducted in 2009 and 2010, corresponding to the drought and flood seasons,
Marcelo Gomes da Silva   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

A Review of the Isotope System of Cadmium and Its Applications in Geosciences and Environmental Sciences

open access: yesYankuang ceshi, 2013
Cadmium is a typical chalcophile element which occurs in various sulfide deposits. In the environmental system, cadmium as the nutritional requirement is utilized for the growth of microorganisms, and its cycle is greatly affected by the biological ...
WANG Dan-ni   +4 more
doaj  

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

How the Marsden Fund has failed to achieve its full potential in the ESA panel: evidence of limitations in scope, biased outcomes, and futile applications [PDF]

open access: yes, 2014
We have analysed the scope of proposals funded by the ‘Earth Sciences and Astronomy’ (ESA) panel of the Marsden Fund for the period 2004 to 2013.
Bryan, Karin R., Lowe, David J.
core   +1 more source

Welcome to Journal of Ethnobiology and Ethnomedicine [PDF]

open access: yes, 2005
Ethnobiology is a multidisciplinary field of study that draws on approaches and methods from both the social and biological sciences. Ethnobiology aims at investigating culturally based biological and environmental knowledge, cultural perception and ...
Leimar Price, L.   +2 more
core   +3 more sources

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