Results 141 to 150 of about 4,106,632 (313)

Local Economies, Trade, and Global Sustainability [PDF]

, 1999
Bioregional and "ecological economics" theory describes the growth of local economic linkages as vital to move post-industrial economies in the direction of sustainability.
Perkins, Patricia E. (Ellie)
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

AI and climate resilience governance

iScience
Summary: While artificial intelligence (AI) offers promising solutions to address climate change impacts, it also raises many application limitations and challenges.
Sara Mehryar, Vahid Yazdanpanah, Jeffrey Tong   +2 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Protocol for the removal of polyvinyl chloride microplastics from water using activated jute stick charcoal

STAR Protocols
Summary: We present a protocol to remove polyvinyl chloride-based microplastics (MPs) from aquatic environments using jute stick activated charcoal (JSAC) as an adsorbent.
Nur Alom, Tapati Roy, Tanny Sarkar, Md Rasel, Md Sanwar Hossain, Mamun Jamal   +5 more
doaj   +1 more source

The disconnect between researcher ambitions and reality in achieving impact in the Earth & Environmental Sciences - author survey. [PDF]

F1000Res, 2021
Kelly A, Gardner V, Gilbert A.
europepmc   +1 more source

International collaboration schemes in earth and environmental sciences : IGEC programmes and UNESCO IHP [PDF]

There is a lack of studies that investigate how internationalization of science can effectively contribute to the globalization of environmental knowledge.
Jappe-Heinze, Arlette
core  

Observing Environments [PDF]

, 2012
> Context • Society is faced with “wicked” problems of environmental sustainability, which are inherently multiperspectival, and there is a need for explicitly constructivist and perspectivist theories to address them.
Alrøe, Hugo Fjelsted, Noe, Egon
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Rainwater Harvesting for Agricultural Irrigation: An Analysis of Global Research [PDF]

, 2019
Within a context of scarce water resources for agriculture, rainwater harvesting constitutes a promising alternative that has been studied by different disciplines in recent years.
Aznar Sánchez, José Ángel, Batlles delaFuente, Ana, Fidelibus, Maria Dolores, Velasco Muñoz, Juan Francisco   +3 more
core   +1 more source