Results 51 to 60 of about 1,477,177 (315)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Suppression of Environmental Science

open access: yesAmerican Journal of Law & Medicine, 2004
There is a long history of attacks on scientists. During the Inquisition, the Roman Catholic Church charged Galileo with heresy and, after imprisonment and threats of torture, forced him to renounce his theory that the sun, not the earth, was the center of the universe.
openaire   +4 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Editorial: Current Research on Soil Science and Related Aspects of Environmental Sciences in Galicia

open access: yesSpanish Journal of Soil Science, 2023
Avelino Núñez-Delgado   +2 more
doaj   +1 more source

Analysis of the influence of environmental parameters on methane flux from floodplains and lakes in the Abobral River, Pantanal, Brazil

open access: yesRevista Ambiente & Água, 2016
This study evaluates the influence of physical and chemical characteristics of the water column in the processes that result in methane emissions in the Pantanal. Two surveys were conducted in 2009 and 2010, corresponding to the drought and flood seasons,
Marcelo Gomes da Silva   +3 more
doaj   +1 more source

Natural sciences and environmental issues: a contribution from the philosophy of environmental sciences

open access: yesInternational Journal of Environment and Health, 2017
The environmental issue has been considered a 'starting point' for certain epistemological transformations that aim at rethinking the way of performing science and interpreting the nature-society relationship. In this paper, we will explore controversial disputes in the natural science field through the analysis of a particular case study: the socio ...
Klier, Gabriela Ruth   +5 more
openaire   +3 more sources

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