Results 81 to 90 of about 1,541,248 (268)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

THE DEVELOPMENT OF THE PRINCIPLES AND WAYS OF INCREASING THE EFFECTIVENESS OF BUDGETARY CONTROL IN THE SPHERE OF ECOLOGY OF NATURE

Вестник университета, 2016
The article describes the main approaches to improving the effectiveness of budget control in the sphere of natural resource use ecology, the analysis of the budget cost control, the proposal on organization of the internal plan-fact analysis-monitoring ...
O. Kovalenko
doaj  

Democratizing education: Open schooling engaged the less privileged in environmental sciences. [PDF]

PLoS One, 2022
Wam HK, Goździk A, Aspholm PE, Juńczyk T.   +3 more
europepmc   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Co-Constructing “Third Spaces” for Engagement with and for Minoritized Community Groups and Environmental Scientists

Earth Science, Systems and Society
The demographics of environmental and Earth scientists are not representative of the UK’s multicultural society. We sought to widen diversity and engage equitably through two related engaged research projects, “Walking the Walk” and “Landscape Stories ...
Richard Holliman, Geeta Ludhra, Clare Janet Warren, Anjana Khatwa, Yoseph Araya, Kelly Smith, Janice Ansine, Marcus Peter Sebastian Badger   +7 more
doaj   +1 more source

Swimming and the human microbiome at the intersection of sports, clinical, and environmental sciences: A scoping review of the literature. [PDF]

Front Microbiol, 2022
Puce L, Hampton-Marcell J, Trabelsi K, Ammar A, Chtourou H, Boulares A, Marinelli L, Mori L, Cotellessa F, Currà A, Trompetto C, Bragazzi NL.   +11 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Increasing collaboration between China and India in the environmental sciences to foster global sustainability. [PDF]

Ambio, 2022
Goodale E, Mammides C, Mtemi W, Chen YF, Barthakur R, Goodale UM, Jiang A, Liu J, Malhotra S, Meegaskumbura M, Pandit MK, Qiu G, Xu J, Cao KF, Bawa KS.   +14 more
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

iMESc – an interactive machine learning app for environmental sciences

Frontiers in Environmental Science
As environmental sciences increasingly rely on complex datasets, machine learning (ML) has become crucial for identifying patterns and relationships. However, the integration of ML into workflows can pose challenges due to technical barriers or the time ...
Danilo Cândido Vieira, Danilo Cândido Vieira, Fabiana S. Paula, Luciana Erika Yaginuma, Gustavo Fonseca   +4 more
doaj   +1 more source