Results 81 to 90 of about 4,106,632 (313)

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Visual Analytics for Exploring Changes in Biodiversity [PDF]

open access: yes, 2013
We report on ongoing work in which we are designing a visual interface to a large database of species observation data. Our design allows the data to be explored and visually summarised by space, time and species, helping assess the data's suitability ...
Slingsby, A., van Loon, E.
core   +1 more source

Predictors of oil shocks. Econophysical approach in environmental science

open access: diamond, 2021
Andrii Bielinskyi   +7 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Evapotranspiration Assessment by Remote Sensing in Brazil with Focus on Amazon Biome: Scientometric Analysis and Perspectives for Applications in Agro-Environmental Studies

open access: yesHydrology
The Amazon biome plays a crucial role in the hydrological cycle, supplying water vapor for the atmosphere and contributing to evapotranspiration (ET) that influences regional humidity across Brazil and South America.
Daniela Castagna   +6 more
doaj   +1 more source

An innovative South African approach to mentoring novice professionals in Biodiversity Management [PDF]

open access: yesInternational Journal of Evidence Based Coaching and Mentoring, 2013
The impact of invasive alien species is a global concern. In South Africa there are a limited number of trained and experienced Biodiversity professionals therefore mentoring of young scientists is crucial to address the effective management of the ...
Philip Ivey, Hilary Geber, Ingrid Nänni
doaj  

SEAD: Preserving Data for Environmental Sciences in Areas of Climate, Land-Use, and Environmental Management [PDF]

open access: yes, 2013
NSF Funded DataNet Project #OCI0940824 • SEAD goal is to contribute infrastructure to the NSF DataNet Vision that supports data • Access • Sharing • Reuse • Preservation • Direct work with data at the NSF STC NCED (National Center for Earth-
et al, et al   +4 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Isotopes in hydrology and hydrogeology [PDF]

open access: yes, 2019
The structure, status, and processes of the groundwater system, which can only be acquired through scientific research efforts, are critical aspects of water resource management. Isotope hydrology and hydrogeology is a genuinely interdisciplinary science.
Barbieri, Maurizio
core   +1 more source

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