Results 81 to 90 of about 1,477,177 (315)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Tabular strategies for metadata in ecology, evolution, and the environmental sciences. [PDF]

Ecol Evol, 2022
Lortie CJ, Vargas Poulsen C, Brun J, Kui L.   +3 more
europepmc   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Co-Constructing “Third Spaces” for Engagement with and for Minoritized Community Groups and Environmental Scientists

Earth Science, Systems and Society
The demographics of environmental and Earth scientists are not representative of the UK’s multicultural society. We sought to widen diversity and engage equitably through two related engaged research projects, “Walking the Walk” and “Landscape Stories ...
Richard Holliman, Geeta Ludhra, Clare Janet Warren, Anjana Khatwa, Yoseph Araya, Kelly Smith, Janice Ansine, Marcus Peter Sebastian Badger   +7 more
doaj   +1 more source

Editorial: Application of computational tools to health and environmental sciences, Volume II. [PDF]

Front Pharmacol, 2022
Ruiz P, Loizou G.
europepmc   +1 more source

ENVIRONMENTAL SCIENCE & TECHNOLOGY [PDF]

, 1967

openalex   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Quantitative evidence synthesis: a practical guide on meta-analysis, meta-regression, and publication bias tests for environmental sciences. [PDF]

Environ Evid, 2023
Nakagawa S, Yang Y, Macartney EL, Spake R, Lagisz M.   +4 more
europepmc   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Corrigendum: BIIGLE 2.0 - Browsing and Annotating Large Marine Image Collections

Frontiers in Marine Science, 2020
Daniel Langenkämper, Martin Zurowietz, Timm Schoening, Tim W. Nattkemper   +3 more
doaj   +1 more source