Results 81 to 90 of about 12,186,927 (332)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
International recognition for UCT Open Educational Resources: Dr Gina Ziervogel wins OpenCourseWare Excellence Award [PDF]
We here at OpenUCT and the Centre for Educational Technology (CET) are proud to announce that going online with materials from one of her courses has won Dr Gina Ziervogel, a lecturer in the Environmental and Geographical Sciences Department here at UCT,
Goodier, Sarah
core
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Environmental Biotechnology Research Group: Research Report. [PDF]
Environmental biotechnology exploits living organisms (plant, bacteria, fungi, etc) in various applications of waste treatment and remediation of pollutants.
Faculty of Biotechnology & Biomolecular Sciences, Environmental Biotechnology Research Group
core +2 more sources
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Arkansas Small-Grain Cultivar Performance Tests 2004-2005 [PDF]
Small-grain cultivar performance tests are conducted each year in Arkansas by the Arkansas Agricultural Experiment Station, Department of Crop, Soil and Environmental Sciences.
Bacon, R. K. +2 more
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Cadmium is a typical chalcophile element which occurs in various sulfide deposits. In the environmental system, cadmium as the nutritional requirement is utilized for the growth of microorganisms, and its cycle is greatly affected by the biological ...
WANG Dan-ni +4 more
doaj
A new scenario framework for climate change research: background, process, and future directions [PDF]
The scientific community is developing new global, regional, and sectoral scenarios to facilitate interdisciplinary research and assessment to explore the range of possible future climates and related physical changes that could pose risks to human and ...
Arnell, NIgel +14 more
core +3 more sources

