Results 241 to 250 of about 930,563 (304)

Genomic prediction via reaction norm models for pregnancy loss using temperature humidity index in brahman cattle. [PDF]

Transl Anim Sci
Cardona-Cifuentes D, de Albuquerque LG, Aguilar I, Arias M, Camaripano L, Gonzalez-Herrera LG, Mota LFM, Baldi F, Amorim ST.   +8 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Uncovering the Community Structure and Adaptive Characteristics of Soil Protists Across Natural, Semi-Natural and Highly Degraded Habitats. [PDF]

Environ Microbiol
Feng SW, Wang X, Wen P, Lu JL, Wu ZH, Yi X, Shu WS, Liang JL, Jia P, Li JT.   +9 more
europepmc   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Predictions From Evolutionary Theory for Urban Environments. [PDF]

Evol Appl
MacPherson A, Caizergues AE, Savary P, Xu K, Messer PW, Akbar MN, Fortin MJ, Holt RD, Hoi AG, Mideo N, Ness R, Peres-Neto PR, Santangelo JS, Johnson MTJ.   +13 more
europepmc   +1 more source

Selection Signatures and Genetic Divergence in Hotan Black and F2 Yeonsan Ogye Chickens. [PDF]

Animals (Basel)
Turxunjan N, Liu Y, Liu M, Liu T, Hou W, Wang H.   +5 more
europepmc   +1 more source

Repeatability Estimation of Some Productive Traits of Racing Homer Pigeons (Columba livia domestica) in Bangladesh. [PDF]

Vet Med Sci
Tinni SD, Haque MN, Mia MM, Dipu DCC, Nath TC.   +4 more
europepmc   +1 more source

Evolution of species' range and niche in changing environments. [PDF]

Proc Natl Acad Sci U S A
Polechová J.
europepmc   +1 more source

Improving cancer care while reducing its carbon footprint: GHG-mitigating strategies highlighted at ESMO 2025. [PDF]

BJC Rep
Delaye M, Matte P, Turpin A, Ducrot C, Dumont S, Petit PF, Piffoux M.   +6 more
europepmc   +1 more source