Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Hydrogenolysis of Glycerol to Propylene Glycol: Energy, Tech-Economic, and Environmental Studies. [PDF]
Sun P +12 more
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A Data‐Driven History of Gloucester's Fisheries Architecture
This article presents the methods and preliminary results of research into the socio‐ecological history of the Gloucester fisheries, with a focus on the interactions between humans and marine ecosystems.
Rafael Sousa Santos, André Tavares
doaj +1 more source
Elemental Speciation Analysis in Environmental Studies: Latest Trends and Ecological Impact. [PDF]
Llaver M +4 more
europepmc +1 more source
An Environmental Resource Inventory of the Township of Little Egg Harbor, with 1992 addendum
This report has been prepared to describe the natural resources of Little Egg Harbor Township, to identify the unique features to be found in the Township and to suggest ways to insure the future conservation of these resources through the local planning
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
I Ka Hana Ka 'Ike: Environmental Field Studies in Hawai'i [PDF]
The purpose of this thesis is to explore environmental education (EE) in Hawai'i through a case-study of the Wildlands Studies: Hawai'i program.
Crouch, Kerry
core +1 more source
A method for bivalve shells characterization by FT-IR photoacoustic spectroscopy as a tool for environmental studies. [PDF]
Giordano L +5 more
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source

