Results 91 to 100 of about 2,198,845 (262)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Emission factors of CO2, CO and CH4 from Sumatran peatland fires in 2013 based on shipboard measurements

open access: yesTellus: Series B, Chemical and Physical Meteorology, 2017
We observed prominent CO enhancements with simultaneous enhancements of CO2 and CH4 around the Malay Peninsula in South-East Asia from mid-June to mid-August 2013 based on systematic shipboard observations.
Hideki Nara   +5 more
doaj   +1 more source

Environmental Studies of Cyanobacterial Harmful Algal Blooms Should Include Interactions with the Dynamic Microbiome. [PDF]

open access: yesEnviron Sci Technol, 2021
Pound HL   +8 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Socioeconomic factors and future challenges of the goal of limiting the increase in global average temperature to 1.5 °C

open access: yesCarbon Management, 2018
The Paris Agreement has confirmed that the ultimate climate policy goal is to hold the increase in the global average temperature to well below 2 °C above pre-industrial levels and to pursue efforts to limit the increase to 1.5 °C. Moving the goal from 2
Jing-Yu Liu   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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