Results 31 to 40 of about 1,485,059 (284)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A tool for sustainability impact assessment (ToSIA)of forest-wood chains linked with a database of sustainability indicators collected within the EFORWOOD project [PDF]

, 2009
Within the EFORWOOD project new approaches to assess the sustainability impacts of forest-wood chains (FWC) using indicators of environmental, social and economic sustainability were ...
Cerny, Martin, Kneblik, Petr, Lindner, Marcus, Palosuo, Taru, Roubalova, Martina, Savolainen, Mikko, Suominen, Tommi, Verweij, Peter, Vötter, Diana, Werhahn-Mees, Wendelin, Zudin, Sergey   +10 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Environmental impacts of plastic waste management practices in urban suburbs areas of Zimbabwe

Discover Sustainability
The study was conducted to explore aspects surrounding plastic waste management in Makokoba high-density suburb, Bulawayo, Zimbabwe. Guided by the pragmatic reasoning, the study employed a descriptive cross sectional design. Referral sampling was used to
Steven Jerie, Amato Chireshe, Tapiwa Shabani, Takunda Shabani, Pure Maswoswere, Olivia C. Mudyazhezha, Chengetai Mashiringwani, Lloyd Mangwandi   +7 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Agricultural potential and safety assessment of biochar obtained from river biomass

Scientific Reports
Biochar, a carbon-rich residue produced by controlled biomass decomposition in oxygen-deprived conditions, like pyrolysis or gasification, has gained attention as a soil enhancer for improving fertility and sequestering carbon. In this study, we analyzed
Elena Riva, Maria Chiara Rosace, Biagio Rimmaudo, Cristina Menta, Giovanna Visioli, Alessio Malcevschi, Annamaria Buschini   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Residents’ perceptions towards illegal household solid waste disposal: A case of Chegutu, Zimbabwe

Smart Construction and Sustainable Cities
Solid waste management has been a daunting problem in Zimbabwe over the past few years. The research sought to examine residents’ knowledge, attitudes and perceptions towards illegal household solid waste disposal in ward 8, Chegutu.
Tatenda Musasa, Amato Chireshe, Steven Jerie, Thelma Machisi, Tapiwa Shabani, Takunda Shabani   +5 more
doaj   +1 more source