Results 41 to 50 of about 476,820 (302)

Taking lead for sustainability: Environmental managers as institutional entrepreneurs [PDF]

, 2020
This paper aims to identify critical events that have affected the professionalization process of environmentalsustainability professionals in the Swedish Architecture, Engineering, and Construction (AEC) industry.
Månsson, Stina,, Gluch, Pernilla, Stina Månsson, M\ue5nsson, Stina, Pernilla Gluch, Gluch, Pernilla,   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Residents’ perceptions towards illegal household solid waste disposal: A case of Chegutu, Zimbabwe

Smart Construction and Sustainable Cities
Solid waste management has been a daunting problem in Zimbabwe over the past few years. The research sought to examine residents’ knowledge, attitudes and perceptions towards illegal household solid waste disposal in ward 8, Chegutu.
Tatenda Musasa, Amato Chireshe, Steven Jerie, Thelma Machisi, Tapiwa Shabani, Takunda Shabani   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Social-ecological systems approach in drought-food insecurity nexus research

npj Sustainable Agriculture
Drought is increasingly seen as the next “pandemic,” threatening global populations and progress towards achieving zero hunger by 2030. Although drought and food security are well-researched, no studies synthesize the progress and gaps in drought-food ...
Debashis Roy, Yollanda Chepkoech Korir, Steven A. Gillespie, Md Sarwar Hossain   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Impacts of solid waste management strategies in urban high density suburbs: a case of Amaveni suburb, Kwekwe, Zimbabwe

Discover Environment
Improper solid waste management is one of the causes of environmental and health problems in many cities worldwide. It is in this context that the study aimed to determine the solid waste management strategies used in Amaveni suburbs in Kwekwe, Zimbabwe ...
Chireshe Amato, Steven Jerie, Timothy Vurayayi Mutekwa, Tapiwa Shabani, Takunda Shabani, Muyambo Tafadzwa   +5 more
doaj   +1 more source

Target proteins reprogrammed by As and As + Si treatments in Solanum lycopersicum L. fruit

BMC Plant Biology, 2017
Background Arsenic is an important contaminant of many arable soils worldwide, while silicon, one of the most abundant elements in the earth’s crust, interacts with As in the context of plant metabolism.
Marta Marmiroli, Francesca Mussi, Davide Imperiale, Nelson Marmiroli   +3 more
doaj   +1 more source

Carboxypeptidase G and pterin deaminase metabolic pathways degrade folic acid in Variovorax sp. F1

BMC Microbiology, 2022
Background Folic acid (FA) is a synthetic vitamin (B9) and the oxidized form of a metabolic cofactor that is essential for life. Although the biosynthetic mechanisms of FA are established, its environmental degradation mechanism has not been fully ...
Yungmi You, Yuki Doi, Norifumi Maeda, Shunsuke Masuo, Norio Takeshita, Naoki Takaya   +5 more
doaj   +1 more source