Results 101 to 110 of about 1,497,264 (313)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Environmental Assessment and Strategic Technology Choice: The Case of Renewable Transport Fuels

open access: yes, 2008
The scale of the required changes is huge, and time is limited if we are to avoid the most severe effects of climate change. To reduce greenhouse gas emissions from road transport, several fuels and electricity originating from renewable energy sources ...
Hillman, Karl
core  

Tier I General Technology Guidance for Environmental Technology

open access: yes, 2000
This document details Tier I of the Technology Acceptance Reciprocity Partnership (TARP) and is intended to provide vendor guidance for development of credible data pertaining to all environmental technology classes and establish an integrated protocol ...

core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Environmental liability, policy and technology in real estate development [PDF]

open access: yes, 2002
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning; and, (S.M.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2002.Includes bibliographical references (p.
Meherik, Deryk.
core  

Short-Term and Long-Term Technology Needs/Matching Status at Idaho National Engineering and Environmental Laboratory [PDF]

open access: yes, 1999
This report identifies potential technology deployment opportunities for the Environmental Management (EM) programs at the Idaho National Engineering and Environmental Laboratory (INEEL).
Claggett, S. L.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy