Results 121 to 130 of about 14,242,361 (316)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Representing accessibility in long-term household decisions evidence from vehicle ownership and residential location-related choice models [PDF]

open access: yes, 2018
Thesis: S.M. in Transportation, Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, 2018.Cataloged from PDF version of thesis.Includes bibliographical references (pages 80-83).This study examines variations in ...
He, He (Civil and environmental engineer) Massachusetts Institute of Technology
core  

The utilization of technology in environmental education

open access: yesCurricula
Environmental education is crucial for constructing public awareness regarding environmental issues and realizing Sustainable Development Goals (SDGs).
Hamida Nurul Azizah
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Choice modeling with observed and unobserved information search

open access: yes, 2019
Thesis: S.M. in Transportation, Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, 2019Cataloged from PDF version of thesis.Includes bibliographical references (pages 73-80).This thesis contributes to the continuous
Xie, Yifei,(Scientist in civil and environmental engineering)Massachusetts Institute of Technology.
core  

The role of the aerodynamic modifications of the shapes of tall buildings [PDF]

open access: yes, 2011
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2011.Cataloged from PDF version of thesis.Includes bibliographical references.With the advances in technology, recent tall building design has undergone a
Lee, Jooeun, S.M. Massachusetts Institute of Technology
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Numerical simulation of mixing in viscous-fingering displacements [PDF]

open access: yes, 2010
Thesis (S.M. in Transportation)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2010.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Jha, Birendra. S.M. Massachusetts Institute of Technology
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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