Results 61 to 70 of about 436,578 (316)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

«ECOLOGICAL BOOMERANG» EFFECT IN HOSPITAL ENVIRONMENT

Вестник Донского государственного технического университета, 2018
Some dangerous, in terms of the man-made ecosystem operation, events in the hospital environment are presented. The microbiological factor, its transformation in the course of the diagnostic and treatment process, and human health implications are ...
Besarion C. Meskhi, Vyacheslav A. Zimenko, Olga V. Dymnikova   +2 more
doaj  

The contribution of pulses to net zero in the UK

Environmental Research: Food Systems
The UK agrifood sector is estimated to be responsible for a quarter of the UK’s territorial greenhouse gas emissions, making it a priority sector for the UK’s net zero commitments by 2050.
Marcus Horril, Rosanne Maguire, John Ingram   +2 more
doaj   +1 more source

Life cycle benzophenone 1 exposure induces anxiety- and depression-like behaviors in zebrafish via endoplasmic reticulum stress-mediated dopaminergic system dysfunction

Environmental Chemistry and Ecotoxicology
Environmental exposure to benzophenones (BPs) has emerged as a potential risk factor for the comorbidity of anxiety and depression. Among them, BP1 has attracted increasing attention due to its potential neurotoxic effects.
Zhipeng Qi, Peng Li, Xiang Gao, Qiuchen Wu, Keying Li, Zhuoyi Xie, Xilan Xia, Tianchen Wang, Xiangrong Zhou, Jianan Li, Xinying Zhao, Hui Yuan, Weiyi Song   +12 more
doaj   +1 more source

Environmental transformation of natural and engineered carbon nanoparticles and implications for the fate of organic contaminants

, 2018
Environmental transformation of carbon nanoparticles can significantly affect their transport, fate, and effects. The last decade of environmental nano-science has often focused on understanding the behavior of well-defined engineered carbon ...
Sigmund, Gabriel (University of Vienna), Jiang, Chuanjia (Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University), Hofmann, Thilo (University of Vienna), Chen, Wei (Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University)   +3 more
core   +1 more source

RTP: One effective platform to probe reactive compound transformation products and its applications for a reactive plasticizer BADGE

, 2021
Reactive compounds, such as covalent toxicants/drugs, have their ubiquitous occurrences and are known to react with protein or DNA in human beings, but their reactions with endogenous metabolites are rarely understood.
Fang, Mingliang, Wang, Yulan, Huan, Tao, Zheng, Jie, Gao, Bei, Liu, Min, Fei, Xunchang, Jiang, Jie   +7 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Empirical estimates of installed capacity density for solar photovoltaic and onshore and offshore wind power plants

Environmental Research: Infrastructure and Sustainability
Large-scale deployment of wind and solar power is essential for climate change mitigation but requires substantial land and offshore area due to their relatively low installed capacity densities.
Austin Covey, Rylee Pupa, Matt Lai, Atherv Gole, Nick Randazzo, Brianna Lee, Sydney Litvin, Sarah MacGregor, Lizzy Mau, Eliana Stone, Yuli Xue, Ethan Takekawa, Matthieu Huy, Grace Wu, Ranjit Deshmukh   +14 more
doaj   +1 more source

Digital Soil Information System for Ireland – Scoping Study [PDF]

, 2007
This synthesis report has been prepared as part of the Environmental Research Technological Development and Innovation (ERTDI) Programme under the Productive Sector Operational Programme 2000-2006. This programme is financed by the Irish Government under
Fealy, Reamonn, Daly, Karen M.
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source