Results 11 to 20 of about 3,509 (186)

Circulating Cell-Free DNA of Bovine Leukemia Virus: A Promising Biomarker for Enzootic Bovine Leukosis. [PDF]

Microbiol Immunol
Bovine leukemia virus (BLV) causes Enzootic bovine leukosis (EBL) in approximately 1%–5% of infected cattle after a long latent period. Few biomarkers effectively distinguish non‐EBL from EBL cattle.
Jahan MI, Jahan MI, Inenaga T, Makimoto S, Hossain MB, Matsuoka Y, Sithi SN, Rajib SA, Ansori ANM, Sugata K, Imakawa K, Kobayashi T, Satou Y.   +12 more
europepmc   +3 more sources

Enzootic bovine leukosis caused by bovine leukemia virus classified as Group C based on viral whole genome sequencing in a 23-month-old Holstein-Friesian heifer. [PDF]

J Vet Med Sci, 2023
A 23-month-old Holstein-Friesian heifer presented with inactivity and diarrhea. On physical examination, no enlargement of superficial lymph nodes was observed. Hematological examination revealed lymphocytosis.
Daiji Y, Maezawa M, Ishikawa K, Chambers JK, Uchida K, Inokuma H.   +5 more
europepmc   +2 more sources

An Update of Epidemiological Trends in Enzootic Bovine Leukosis in Italy and an Analysis of Risk Factors Associated with Infection Persistence. [PDF]

Pathogens
In 2017, the Commission Implementing Decision (European Union [EU]) 2017/1910 officially declared Italy to be enzootic bovine leukosis (EBL)-free. The Commission Delegated Regulation (EU) 2020/689 laid criteria to maintain an official disease-free status.
Righi C, Iscaro C, Petrini S, Scoccia E, Pirani S, Fiorucci A, Lomolino R, Feliziani F.   +7 more
europepmc   +2 more sources

Characterization of miRNAs in Milk Small Extracellular Vesicles from Enzootic Bovine Leukosis Cattle. [PDF]

Int J Mol Sci, 2022
Enzootic bovine leukosis (EBL) is a B-cell lymphosarcoma caused by the bovine leukemia virus (BLV). Most BLV-infected cattle show no clinical signs and only some develop EBL. The pathogenesis of EBL remains unclear and there are no methods for predicting
Tsukada F, Takashima S, Wakihara Y, Kamatari YO, Shimizu K, Okada A, Inoshima Y.   +6 more
europepmc   +2 more sources

Serum bta-miRNA-375 as a potential biomarker for the early diagnosis of enzootic bovine leukosis. [PDF]

PLoS One
To identify a biomarker for the early diagnosis of enzootic bovine leukosis (EBL) caused by bovine leukemia virus (BLV), we investigated the expression of a microRNA, bta-miR-375, in cattle serum. Using quantitative reverse-transcriptase PCR analysis, we
Murakami K, Matsunaga T, Matsuzaki T, Naruke Y, Miyauchi S, Kobayashi S, Yoneyama S, Sakai Y, Ichijo T, Hirata TI, Kimura A, Chiba Y, Matsuda KI, Yamada S, Hikono H.   +14 more
europepmc   +2 more sources

Enzootic bovine leukosis in a 21-month-old Japanese Black cow with high susceptibility. [PDF]

J Vet Diagn Invest, 2022
A 21-mo-old Japanese Black beef cow had swollen mandibular and superficial cervical lymph nodes. Fine-needle aspiration cytology of the superficial cervical lymph node revealed large lymphoblasts with mitoses present.
Maezawa M, Sakaguchi K, Tagaino Y, Fujii Y, Akagami M, Kawakami J, Watanabe KI, Kobayashi Y, Ogawa H, Inokuma H.   +9 more
europepmc   +2 more sources

A clinical case of enzootic bovine leukosis in a Holstein cow with minor clonality of B-cell in the peripheral blood. [PDF]

J Vet Med Sci
A 4-year 9-month-old Holstein-Friesian dairy cow presented with anorexia. On physical examination, swelling of superficial lymph nodes, pelvic masses, and prolonged urination posture after urinating a small amount were noted.
Maezawa M, Kikuzawa M, Takiguchi A, Saito R, Chambers JK, Uchida K, Inokuma H.   +6 more
europepmc   +2 more sources

Identification of Potential mRNA Biomarkers in Milk Small Extracellular Vesicles of Enzootic Bovine Leukosis Cattle. [PDF]

Viruses, 2022
Enzootic bovine leukosis (EBL) is a disease caused by bovine leukemia virus (BLV); only a small percentage of BLV-infected cattle develop EBL and present with B-cell lymphosarcoma.
Hiraoka M, Takashima S, Wakihara Y, Kamatari YO, Shimizu K, Okada A, Inoshima Y.   +6 more
europepmc   +2 more sources

Monoclonal proliferation of B-cells with two integration sites of bovine leukemia virus proviral DNA in cattle with enzootic bovine leukosis. [PDF]

J Vet Med Sci
The present study analyzed B-cell clonality and bovine leukemia virus (BLV) provirus integration sites in cattle with enzootic bovine leukosis (EBL) having BLV proviral copy numbers less or greater than the number of bovine nucleated cells.
Maezawa M, Takezawa S, Sakaguchi-Maezawa K, Tanaka Y, Watanabe KI, Kobayashi Y, Inokuma H.   +6 more
europepmc   +2 more sources

Infection with bovine leukemia virus belonging to group A or B-1 contributes more strongly to the development of enzootic bovine leukosis in young cattle than the presence of bovine lymphocyte antigen-DRB3 susceptibility alleles. [PDF]

Arch Virol
In this study, we compared the effects of different bovine leukemia virus (BLV) strains and bovine lymphocyte antigen (BoLA)-DRB3 alleles in cattle with enzootic bovine leukosis (EBL) aged either
Fujii Y, Maezawa M, Akagami M, Kawakami J, Fujimoto Y, Inokuma H.   +5 more
europepmc   +2 more sources