Brush border digestion : development of a physiologically relevant in vitro model : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Physiology at Massey University, Manawatū, New Zealand [PDF]
, 2018 Chapter Two has, in part, been published in the Springer publication, Reviews of Physiology, Biochemistry and Pharmacology, but the Author retains the right to publish the material in any collection consisting of the Author's own works: Hooton, D ...
Hooton, Diane Frances
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Molecularly Engineered Self-Assembling Membranes for Cell-Mediated Degradation [PDF]
, 2015 The use of peptide engineering to develop self-assembling membranes that are responsive to cellular enzyme activities is reported. The membranes are obtained by combining hyaluronan (HA) and a rationally designed peptide amphiphile (PA) containing a ...
Aimes +65 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Functional Assemblages of Collembola Determine Soil Microbial Communities and Associated Functions
Frontiers in Environmental Science, 2019 Soil processes such as decomposition are mainly performed by soil biota. Although soils worldwide are extremely biodiverse, the relationship between decomposers (fauna and microorganisms), and ecosystem function is poorly understood.
Sékou F. M. Coulibaly +6 more
doaj +1 more source
The Urea Carboxylase and Allophanate Hydrolase Activities of Urea Amidolyase Are Functionally Independent [PDF]
, 2016 Urea amidolyase (UAL) is a multifunctional biotin-dependent enzyme that contributes to both bacterial and fungal pathogenicity by catalyzing the ATP-dependent cleavage of urea into ammonia and CO2.
Bahler +48 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Agriculture, 2012 Earthworm biomass and production in savannas are limited by seasonal precipitation and the lack of organic and nutrient resources; I hypothesize that after a long-term protection of savanna from fire and agricultural activities drastic changes in the ...
Danilo López-Hernández
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Enzyme activity in terrestrial soil in relation to exploration of the Martian surface Semiannual progress report, 1 Jul. - 31 Dec. 1967 [PDF]
Enzyme behavior in nonclassical systems, surface pH estimation in soils, and enzymatic activities in stored and geologically preserved ...
Mc Laren, A. D., Skujins, J. J.
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Formalin Exposure on the Rats Feeding Diet on Antioxidant Enzymatic activity and Oxidative Damage of Rats Liver Tissue [PDF]
, 2015 Using formalin or formaldehyde as a illegal preservative on food and ingredient Is very danger for health because formalin is a toxic and carcinogenic substance that potent as a sources of reactive oxygen species (ROS) and free radical ...
Aulaniam , A., Mahdi, Chanif
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