Results 211 to 220 of about 681,027 (341)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Establishment of neuronal and glial competence of neural stem cells requires distinct enzymatic activities of TET enzymes. [PDF]
Ebert BC +6 more
europepmc +1 more source
Identification of flexible Pif1-DNA interactions and their impacts on enzymatic activities. [PDF]
Li J +11 more
europepmc +1 more source
Antioxidant activity of Tinospora cordifolia leaf extracts through non-enzymatic method
Praveen Nagella
openalex +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Wounding causes rapid, intense upregulation of glycolytic and fermentative genes and enzymatic activities in harvested sugarbeet roots. [PDF]
Fugate KK +4 more
europepmc +1 more source
Response of microbiota to exogenous inoculation improved the enzymatic activities of medium-temperature Daqu. [PDF]
Pan Q +7 more
europepmc +1 more source

