Results 221 to 230 of about 681,027 (341)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

IDO Activation Affects BDNF/TrkB Signaling Pathway, Oxidative Stress, and Mitochondrial Enzymatic Activities in Temporal Lobe Epilepsy. [PDF]

Curr Issues Mol Biol
Xu J, Wei L, Fu J, Kong Z, Cai L.
europepmc   +1 more source

Phenolic Compounds and Antioxidant and Anti-Enzymatic Activities of Selected Adaptogenic Plants from South America, Asia, and Africa. [PDF]

Molecules, 2023
Gębalski J, Małkowska M, Graczyk F, Słomka A, Piskorska E, Gawenda-Kempczyńska D, Kondrzycka-Dąda A, Bogucka-Kocka A, Strzemski M, Sowa I, Wójciak M, Grzyb S, Krolik K, Ptaszyńska AA, Załuski D.   +14 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Role of the CBM11, Fn3, and CBM3 Domains in Enhancing the Multifunctional Enzymatic Activities of Glycoside Hydrolase Family 5 from <i>Paenibacillus curdlanolyticus</i> B-6. [PDF]

J Microbiol Biotechnol
Fatmawati NV, Singkhala A, Ketbot P, Baramee S, Waeonukul R, Tachaapaikoon C, Uke A, Kosugi A, Ratanakhanokchai K, Pason P.   +9 more
europepmc   +1 more source

Metal Release from Microplastics to Soil: Effects on Soil Enzymatic Activities and Spinach Production. [PDF]

Int J Environ Res Public Health, 2023
Santini G, Memoli V, Vitale E, Di Natale G, Trifuoggi M, Maisto G, Santorufo L.   +6 more
europepmc   +1 more source

In vitro studies of Thiopurine S-Methyltransferase: Ligand binding interactions and development of a new enzymatic activity assay for TPMTwt, TPMT*6 and TPMT*8

, 2015
Lovisa Hemmingsson, Johan Klasén
openalex   +1 more source

Potential of Indigenous Enzymatic Activities, Nitric Oxide and Ceruloplasmin in Bovine Milk to Diagnose Subclinical Mastitis

, 2011
Ujjwal Kumar De, Reena Mukherjee
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Toxic dinoflagellate <i>Prorocentrum cordatum</i> affects the filtration rate and enzymatic activities of Chinese razor clam (<i>Sinonovacula constricta</i>). [PDF]

PeerJ
Tang Y, Jiang Z, Liao Y, Shou L, Zeng J, Zhang R, Li C.   +6 more
europepmc   +1 more source