Results 231 to 240 of about 6,659,593 (302)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

A Retrospective Analysis of ADAMTS13 Enzymatic Activity Results in a Population With Thrombotic Thrombocytopenic Purpura Disease in the Arabian Gulf and Colombia (APOLO Study). [PDF]

Cureus
Edris S, Aktham Y, Mekky A, Chouikrat MZ, Al Mahdi HB, Younis M, Cortés MA, Vargas MF, Fahmy M.   +8 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Icariin Enhances the Enzymatic Activity of N-acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD-1 Blockade Efficacy in Tumor Suppression. [PDF]

Adv Sci (Weinh)
Qiao S, Yang L, Hao H, Ding Q, Ding F, Chen Z, Zhang J, He Y, Li M, Xu J, Wang C, Lu A, Li F.   +12 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

PELP1 coordinates the modular assembly and enzymatic activity of the rixosome complex. [PDF]

Sci Adv
Gordon J, Kaminski AM, Bommu SR, Skrajna A, Petrovich RM, Pedersen LC, McGinty RK, Warren AJ, Stanley RE.   +8 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Monitoring insecticide resistance in cotton leafhopper in relation to enzymatic activity in major cotton growing areas of central India. [PDF]

Sci Rep
Chinna Babu Naik V, Chowdary LR, Nagaharish G, Nagarare VS, Murthy JSV, Supreeth GS, Madhu TN, Kumbhare S, Prasad YG, Chandrashekara KM.   +9 more
europepmc   +1 more source

Enzymatic activity of PBP1B is required for growth rate-independent ppGpp-mediated resistance to PBP2 inhibitors in E. coli. [PDF]

J Bacteriol
Anderson SE, Mack IE, Levin PA.
europepmc   +1 more source

Riparian Forest Restoration Drives the Recovery of Soil Chemistry, Microbial Community Structure, and Enzymatic Activity in the Itaipu Reservoir Protection Zone. [PDF]

Microorganisms
Machineski GDS, Menoncin AS, Leonardo HCL, Colozzi Filho A.   +3 more
europepmc   +1 more source