Results 291 to 300 of about 1,010,321 (332)

Branching and molecular weight in levan: A detailed analysis of structural variability and enzymatic hydrolysis susceptibility

open access: hybrid
Alfonso Miranda‐Molina   +6 more
openalex   +1 more source

Integrative Omics Defines Metabolic Biomarkers and Genetic Regulatory Mechanisms of Mortality Risk

open access: yesAdvanced Science, EarlyView.
Understanding mortality mechanisms remains a fundamental challenge. Through multi‐omics analysis of a three‐generation chicken model, are identified 45,585 mQTLs and establish a 16‐metabolite predictor of mortality. An inflammation‐growth trade‐off and evolutionarily conserved pathways involving butyrate–microbiota interactions and L‐cysteine's dual ...
Peihao Liu   +10 more
wiley   +1 more source

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

open access: yesAdvanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu   +8 more
wiley   +1 more source

Colored Plastic Pollution Reshapes Aquatic Microbial Community and Resistance Profile via Divergent Pseudonatural Dissolved Organic Matter

open access: yesAdvanced Science, EarlyView.
By altering the quantity and chemical composition of polyethylene‐derived dissolved organic matter, plastic color dynamically regulates bacterial metabolic interactions, thereby reshaping community resistance expression and facilitating the dissemination of antibiotic resistance.
Shuting Fang   +7 more
wiley   +1 more source

Evolution of Multivalent Aptamer Corona for High‐Throughput Multiplexed Detection of Multiple Cancers

open access: yesAdvanced Science, EarlyView.
A multivalent aptamer corona is evolved via established ProteoFish‐SELEX (systematic evolution of ligands by exponential enrichment) for high‐throughput multiplexed detection of multiple cancers. Clinical validation using multivalent aptamer corona demonstrated high accuracy and specificity in multiplexed detection of ovarian, lung, and colorectal ...
Mengjie Wang   +10 more
wiley   +1 more source

Autonomous Polymer Frameworks for Sustainable Tissue‐Interfaced Plastic Bioelectronics

open access: yesAdvanced Science, EarlyView.
This review focuses on plastic bioelectronic systems integrated with autonomous polymer frameworks (auto‐POFs) and summarizes recent progress in this field. It provides an in‐depth analysis of the design strategies and operational mechanisms of auto‐POFs, highlighting their pivotal role in enhancing the sustainability and interfacial adaptability of ...
Elvis K. Boahen   +8 more
wiley   +1 more source

Graphing the Green route: Enzymatic hydrolysis in sustainable decomposition. [PDF]

open access: yesCurr Res Microb Sci
Singh R   +7 more
europepmc   +1 more source

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