Results 291 to 300 of about 1,010,321 (332)
Integrative Omics Defines Metabolic Biomarkers and Genetic Regulatory Mechanisms of Mortality Risk
Understanding mortality mechanisms remains a fundamental challenge. Through multi‐omics analysis of a three‐generation chicken model, are identified 45,585 mQTLs and establish a 16‐metabolite predictor of mortality. An inflammation‐growth trade‐off and evolutionarily conserved pathways involving butyrate–microbiota interactions and L‐cysteine's dual ...
Peihao Liu +10 more
wiley +1 more source
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu +8 more
wiley +1 more source
Obtaining higher yield and quality rapeseed protein: complex enzymatic hydrolysis assisted alkaline water extraction of cold pressed-extracted rapeseed meal. [PDF]
Du Z +6 more
europepmc +1 more source
By altering the quantity and chemical composition of polyethylene‐derived dissolved organic matter, plastic color dynamically regulates bacterial metabolic interactions, thereby reshaping community resistance expression and facilitating the dissemination of antibiotic resistance.
Shuting Fang +7 more
wiley +1 more source
Optimizing the treatment and valorization of spent coffee grounds (SCGs) through the integration of sequential pretreatment steps, enzymatic hydrolysis, and selective fermentation. [PDF]
Cho EJ +5 more
europepmc +1 more source
A multivalent aptamer corona is evolved via established ProteoFish‐SELEX (systematic evolution of ligands by exponential enrichment) for high‐throughput multiplexed detection of multiple cancers. Clinical validation using multivalent aptamer corona demonstrated high accuracy and specificity in multiplexed detection of ovarian, lung, and colorectal ...
Mengjie Wang +10 more
wiley +1 more source
Step Enzymatic Hydrolysis and <i>In Silico</i> Screening-Assisted Preparation of Bioactive Peptides from Abalone. [PDF]
Liu K +5 more
europepmc +1 more source
Autonomous Polymer Frameworks for Sustainable Tissue‐Interfaced Plastic Bioelectronics
This review focuses on plastic bioelectronic systems integrated with autonomous polymer frameworks (auto‐POFs) and summarizes recent progress in this field. It provides an in‐depth analysis of the design strategies and operational mechanisms of auto‐POFs, highlighting their pivotal role in enhancing the sustainability and interfacial adaptability of ...
Elvis K. Boahen +8 more
wiley +1 more source
Graphing the Green route: Enzymatic hydrolysis in sustainable decomposition. [PDF]
Singh R +7 more
europepmc +1 more source

