Results 181 to 190 of about 4,423,700 (359)

A method for predicting enzyme substrate specificity residues using homologous sequence information. [PDF]

Protein Sci
Mori S, Niide T, Toya Y, Shimizu H.
europepmc   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Prediction of enzyme function using an interpretable optimized ensemble learning framework. [PDF]

Chem Sci
Dhibar S, Basak S, Jana B.
europepmc   +1 more source

Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide.

Clinical Chemistry, 1982
Lorenzo Fossati, Prencipe
semanticscholar   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Dynamics of single enzymes confined inside a nanopore. [PDF]

RSC Chem Biol
Galenkamp NS, van den Noort M, Maglia G.
europepmc   +1 more source

LIBERATION OF AMINO ACIDS FROM RAW AND HEATED CASEIN BY ACID AND ENZYME HYDROLYSIS

, 1948
L. V. Hankes, W.H. Riesen, L.M. Henderson, C.A. Elvehjem   +3 more
openalex   +1 more source

Some properties of the malic enzyme of pigeon liver. 2. Synthesis of malate from pyruvate [PDF]

, 1959
R. G. Stickland
openalex   +1 more source

NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2

FEBS Open Bio, EarlyView.
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper, Sridhar Sreeramulu, Benjamin T. Lanham, Elizabeth M. Engle, David Fushman, Harald Schwalbe   +5 more
wiley   +1 more source

Pancreatic Lipase in Eutectogels as Emerging Materials: Exploring Their Properties and Potential Applications in Biosensing. [PDF]

Biosensors (Basel)
Martínez-Baquero R, Martínez-Tomé MJ, Gómez J, Esquembre R, Mateo CR.   +4 more
europepmc   +1 more source