Semi-Rational Engineering of Formate Dehydrogenase Reveals Loop Dynamics as a Key Determinant of Thermostability. [PDF]
Boonkumkrong R +7 more
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Immobilization of an Invertase Produced by a Bacterium Isolated from the Peach Palm Fruit (<i>Bactris gasipaes</i>): Influence of the Support Material and Biochemical Characterization. [PDF]
Saraiva LS +9 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Reactivity of mammalian lipoxygenases (ALOX isoforms) with phospholipids, biomembranes and lipoproteins. [PDF]
Chen X +8 more
europepmc +1 more source
Lipase Stability in Structured Lipid Synthesis: The Interplay of Substrate Characteristics and Strategies to Improve Its Operational Performance-A Critical Review. [PDF]
Lee EL +4 more
europepmc +1 more source
Screening of Ionic Liquids and Deep Eutectic Solvents for Enhancing the Activity and Stability of Fungal Laccase: Empowering Kinetic Parameters and Long-Term Conservation. [PDF]
Haj Kacem S +5 more
europepmc +1 more source
Roles of acidic residues in SpeG acetyltransferases-insights into importance for kinetic activity and polyamine binding in allosteric and acceptor sites. [PDF]
Leiva Martel HN +6 more
europepmc +1 more source

