Results 201 to 210 of about 6,423,279 (401)

Effects of High Levels of Enzyme Blend With Probiotic on Performance, Intestinal Morphology, Microbial Population, and Immune Response in Broiler Chickens. [PDF]

Vet Med Sci
Esmaeili B, Afsharmanesh M, Bami MK.
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

A Peptidoglycan-Remodeling Enzyme Is Critical for Bacteroid Differentiation in Bradyrhizobium spp. During Legume Symbiosis [PDF]

, 2016
Djamel Gully, Daniel Gargani, Katia Bonaldi, Cédric Grangeteau, Clémence Chaintreuil, Joël Fardoux, Van Phuong Nguyen, Roberta Marchetti, Nico Nouwen, Antonio Molinaro, Peter Mergaert, Éric Giraud   +11 more
openalex   +1 more source

Calculation of Heat Capacity Changes in Enzyme Catalysis and Ligand Binding

, 2022
Johan Åqvist, Florian van der Ent
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

miRNA-processing enzyme Dicer is necessary for cardiac outflow tract alignment and chamber septation

, 2009
Ankur Saxena, Clifford J. Tabin
openalex   +1 more source

Enzyme-Mediated Precipitation of Heavy Metals Using Urease Extracted from <i>Sporosarcina pasteurii</i>. [PDF]

Iran J Biotechnol
Joukar A, Mohammadi M, Ghezelbash GR.
europepmc   +1 more source

Retraction Note: Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells

Scientific Reports
Hideyuki Hara, Junji Chida, Keiji Uchiyama, Agriani Dini Pasiana, Etsuhisa Takahashi, Hiroshi Kido, Suehiro Sakaguchi   +6 more
doaj   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source