Results 21 to 30 of about 4,423,700 (359)

dbCAN2: a meta server for automated carbohydrate-active enzyme annotation

open access: yesNucleic Acids Res., 2018
Complex carbohydrates of plants are the main food sources of animals and microbes, and serve as promising renewable feedstock for biofuel and biomaterial production.
Han Zhang   +8 more
semanticscholar   +1 more source

Comparative Study of Single-stranded Oligonucleotides Secondary Structure Prediction Tools

open access: yesBMC Bioinformatics, 2023
Background Single-stranded nucleic acids (ssNAs) have important biological roles and a high biotechnological potential linked to their ability to bind to numerous molecular targets. This depends on the different spatial conformations they can assume. The
Thomas Binet   +4 more
doaj   +1 more source

Clinical Utility of SARS-CoV-2 Antibody Titer Multiplied by Binding Avidity of Receptor-Binding Domain (RBD) in Monitoring Protective Immunity and Clinical Severity

open access: yesViruses, 2023
Conventional serum antibody titer, which expresses antibody level, does not provide antigen binding avidity of the variable region of the antibody, which is essential for the defense response to infection.
Etsuhisa Takahashi   +11 more
doaj   +1 more source

Characterization and engineering of a two-enzyme system for plastics depolymerization

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Deconstruction of recalcitrant polymers, such as cellulose or chitin, is accomplished in nature by synergistic enzyme cocktails that evolved over millions of years.
B. Knott   +21 more
semanticscholar   +1 more source

The alkynyl-containing compounds from mushrooms and their biological activities

open access: yesNatural Products and Bioprospecting, 2023
Mushrooms have been utilized by humans for thousands of years due to their medicinal and nutritional properties. They are a crucial natural source of bioactive secondary metabolites, and recent advancements have led to the isolation of several alkynyl ...
Ji-shuang Qi   +5 more
doaj   +1 more source

Enzymes as chaperones and chaperones as enzymes

open access: yesFEBS Letters, 1998
Chaperones and foldases are two groups of accessory proteins which assist maturation of nascent peptides into functional proteins in cells. Protein disulfide isomerase, a foldase, and ATP‐dependent proteases, responsible for degradation of misfolded proteins in cells, both have intrinsic chaperone activities.
Chen Lu Tsou, Chih-chen Wang
openaire   +3 more sources

Genome-wide study of Cerrena unicolor 87613 laccase gene family and their mode prediction in association with substrate oxidation

open access: yesBMC Genomics, 2023
Background Laccases are green biocatalysts with wide industrial applications. The study of efficient and specific laccase producers remains a priority.
Long-Bin Zhang   +2 more
doaj   +1 more source

The length of ribosomal binding site spacer sequence controls the production yield for intracellular and secreted proteins by Bacillus subtilis

open access: yesMicrobial Cell Factories, 2020
Background Bacillus subtilis is widely used for the industrial production of recombinant proteins, mainly due to its high secretion capacity, but higher production yields can be achieved only if bottlenecks are removed.
Kristina Volkenborn   +5 more
doaj   +1 more source

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

open access: yesNature, 2003
Spike (S) proteins of coronaviruses, including the coronavirus that causes severe acute respiratory syndrome (SARS), associate with cellular receptors to mediate infection of their target cells. Here we identify a metallopeptidase, angiotensin-converting
Wenhui Li   +11 more
semanticscholar   +1 more source

Optimization of physical conditions for the production of thermostable T1 lipase in Pichia guilliermondii strain SO using response surface methodology

open access: yesBMC Biotechnology, 2017
Background Pichia guilliermondii was found capable of expressing the recombinant thermostable lipase without methanol under the control of methanol dependent alcohol oxidase 1 promoter (AOXp 1). In this study, statistical approaches were employed for the
Mary Ladidi Abu   +3 more
doaj   +1 more source

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