Results 31 to 40 of about 6,423,741 (359)

Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.

open access: yesPharmacology and Therapeutics, 2013
Cytochromes P450 (CYP) are a major source of variability in drug pharmacokinetics and response. Of 57 putatively functional human CYPs only about a dozen enzymes, belonging to the CYP1, 2, and 3 families, are responsible for the biotransformation of most
U. Zanger, M. Schwab
semanticscholar   +1 more source

Metabolomics on integrated circuit [PDF]

open access: yes, 2017
We have demonstrated a chip-based diagnostics tool for the quantification of metabolites, using specific enzymes, to study enzyme kinetics and calculate the Michaelis-Menten constant.
Barrett, Michael P.   +3 more
core   +1 more source

Correction to: Molecular, biochemical and kinetic analysis of a novel, thermostable lipase (LipSm) from Stenotrophomonas maltophilia Psi‑1, the first member of a new bacterial lipase family (XIX)

open access: yesJournal of Biological Research - Thessaloniki, 2018
We have recently (8th February 2018) published our article entitled “Molecular, biochemical and kinetic analysis of a novel, thermostable lipase (LipSm) from Stenotrophomonas maltophilia Psi-1, the first member of a new bacterial lipase family (XVIII ...
Maria Parapouli   +8 more
doaj   +1 more source

Kinetic Characterization and X-ray Structure of a Mutant of Haloalkane Dehalogenase with Higher Catalytic Activity and Modified Substrate Range [PDF]

open access: yes, 1996
Conversion of halogenated aliphatics by haloalkane dehalogenase proceeds via the formation of a covalent alkyl-enzyme intermediate which is subsequently hydrolyzed by water.
Dijkstra, Bauke W.,   +7 more
core   +3 more sources

Assaying activity and assessing thermostability of hyperthermophilic enzymes [PDF]

open access: yes, 2001
There is now a wide variety of intra- and extra-cellular enzymes available from organisms growing above 75°C, and having sufficient stability to allow assay well above this temperature.
Akanuma   +22 more
core   +2 more sources

Restriction Enzymes [PDF]

open access: yesCold Spring Harbor Protocols, 2021
Restriction enzymes provided the foundation on which molecular cloning was built, and they remain as essential tools in current recombinant DNA technology. The three classes of restriction enzymes and their features are introduced here.
Michael R, Green, Joseph, Sambrook
openaire   +2 more sources

Soil enzyme activities in the rhizosphere of field-grown sugar beet inoculated with the biocontrol agent Pseudomonas fluorescens F113 [PDF]

open access: yes, 1998
The original publication is available at www.springerlink.com . Copyright Springer DOI : 10.1007/s003740050397Pseudomonas fluorescens F113, which produces the antimicrobial compound 2,4-diacetylphloroglucinol is a prospective biocontrol agent.
Lynch, J.M.   +4 more
core   +1 more source

Comparative Study of Single-stranded Oligonucleotides Secondary Structure Prediction Tools

open access: yesBMC Bioinformatics, 2023
Background Single-stranded nucleic acids (ssNAs) have important biological roles and a high biotechnological potential linked to their ability to bind to numerous molecular targets. This depends on the different spatial conformations they can assume. The
Thomas Binet   +4 more
doaj   +1 more source

Clinical Utility of SARS-CoV-2 Antibody Titer Multiplied by Binding Avidity of Receptor-Binding Domain (RBD) in Monitoring Protective Immunity and Clinical Severity

open access: yesViruses, 2023
Conventional serum antibody titer, which expresses antibody level, does not provide antigen binding avidity of the variable region of the antibody, which is essential for the defense response to infection.
Etsuhisa Takahashi   +11 more
doaj   +1 more source

dbCAN2: a meta server for automated carbohydrate-active enzyme annotation

open access: yesNucleic Acids Res., 2018
Complex carbohydrates of plants are the main food sources of animals and microbes, and serve as promising renewable feedstock for biofuel and biomaterial production.
Han Zhang   +8 more
semanticscholar   +1 more source

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