Results 231 to 240 of about 6,529,404 (392)

Hydrogen sulfide repairs testicular damage induced by heat stress in rats

FEBS Open Bio, EarlyView.
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo, Yupeng Yin, Susu Guo, Xiaoyan Chen, Suyan Xie, Shiqin Chen, Yan Huang   +6 more
wiley   +1 more source

Studies on the Mechanism of Glutamine Synthesis: Evidence for the Formation of Enzyme-bound Activated Glutamic Acid

, 1962
P. R. Krishnaswamy, Vaira Pamiljans, Alton Meister   +2 more
openalex   +1 more source

ACTIVATION OF LYSOSOMAL ENZYMES IN VIRUS-INFECTED CELLS AND ITS POSSIBLE RELATIONSHIP TO CYTOPATHIC EFFECTS [PDF]

, 1963
A. C. Allison, Karin Sandelin
openalex   +1 more source

Dysfunctional tetraspanin 7 (TSP‐7) in Caenorhabditis elegans promotes; increases in average life‐ & health‐span, stress‐induced survival and motility

FEBS Open Bio, EarlyView.
The C. elegans tetraspanin‐7 (tsp‐7) is a homologue of human CD63, which is a negative regulator of autophagy. The C. elegans strain, tm5761, has a dysfunctional (knockout) tsp‐7 gene. When compared to the wild‐type strain, the tm5761 strain shows increased: life‐ and health‐span; thermotolerance, and stress‐induced locomotion.
Brogan Jones, Laurence Seabra, Francesco Michelangeli   +2 more
wiley   +1 more source

Unnatural enzyme activation by a metal-responsive regulatory protein. [PDF]

Chem Sci
Halfin O, Avram L, Albeck S, Unger T, Motiei L, Margulies D.   +5 more
europepmc   +1 more source

The regulation of rat‐liver xanthine oxidase: Activation by proteolytic enzymes [PDF]

, 1968
E. Della Corte, Fiorenzo Stirpe
openalex   +1 more source

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

FEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei, Amir Barzegar Behrooz, Marco Cordani, Mahmoud Aghaei, Negar Azarpira, Daniel J. Klionsky, Saeid Ghavami   +6 more
wiley   +1 more source

Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms. [PDF]

J Biol Chem, 2019
Yadav P, Goyal VD, Gaur NK, Kumar A, Gokhale SM, Jamdar SN, Makde RD.   +6 more
europepmc   +1 more source

Amino acid-activating enzymes in muscle [PDF]

, 1960
R. J. Pennington
openalex   +1 more source

Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate

FEBS Open Bio, EarlyView.
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel, Maurice Tust, Samira Boussettaoui, Dietmar Fischer, Dirk Gründemann   +4 more
wiley   +1 more source