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Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

Not Just an Alternative Energy Source: Diverse Biological Functions of Ketone Bodies and Relevance of HMGCS2 to Health and Disease. [PDF]

Biomolecules
Suresh VV, Sivaprakasam S, Bhutia YD, Prasad PD, Thangaraju M, Ganapathy V.   +5 more
europepmc   +1 more source

Nitric Oxide Inhibition of Glycyl Radical Enzymes and Their Activases. [PDF]

J Am Chem Soc
Cáceres JC, Michellys NG, Greene BL.
europepmc   +1 more source

Safety evaluation of the food enzyme tannase from the non-genetically modified <i>Aspergillus</i> sp. strain TAN 206. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Sramkova M, Van Loveren H, Vernis L, Criado A, Andryszkiewicz M, Cavanna D, Marini E, Liu Y.   +18 more
europepmc   +1 more source

LnDOTA Releasing Probes for Luminescence and Magnetic Resonance Imaging. [PDF]

Inorg Chem
Foster CA, Sneddon D, Hacker L, Sarson ET, Robertson M, Sokolova D, Martin LAW, Allen MF, Khrapichev A, Vincent KA, Hammond EM, Conway SJ, Faulkner S.   +12 more
europepmc   +1 more source

Cluster model study of the mechanism and origins of enantio- and chemoselectivity in non-heme iron enzyme-catalyzed C-H azidation. [PDF]

RSC Adv
Liu H, Chen X, Wu H, She Y, Yang YF.
europepmc   +1 more source

Unveiling the crossroads of STING signaling pathway and metabolic reprogramming: the multifaceted role of the STING in the TME and new prospects in cancer therapies. [PDF]

Cell Commun Signal
Wang S, Qin L, Liu F, Zhang Z.
europepmc   +1 more source

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Specific Activation of Photosensitizer with Extrinsic Enzyme for Precisive Photodynamic Therapy.

Journal of the American Chemical Society, 2022
Delivery of functional proteins into the intracellular space has been a challenging task that could lead to a myriad of therapeutic applications. We report herein a novel bioconjugation strategy for enzyme modification and selective delivery into cancer ...
Junlong Xiong, Jacky C H Chu, W. Fong, Clarence T T Wong, D. K. Ng   +4 more
semanticscholar   +1 more source

Enzyme activation for activator and enzyme activity measurement☆

Biosensors and Bioelectronics, 1993
A new sensing principle of enzyme activation is demonstrated for the determination of glycogen phosphorylase b and its allosteric effector AMP. As the indicator of the phosphorylase catalysed glycogen phosphorolysis, glucose-1-phosphate formation has been detected with an enzyme sequence comprising coentrapped alkaline phosphatase, mutarotase and ...
Wollenberger, Ursula, Scheller, Frieder W.   +1 more
openaire   +3 more sources