Results 191 to 200 of about 1,716,115 (264)

Substrate Exclusion Greenlights Physical Autocatalysis of Enzyme Activity in Membraneless Proto-Organelles. [PDF]

Biomacromolecules
Ahmed T, Verma A, Takayama S.
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

ALDH2 protects against dopaminergic neuronal cell ferroptosis by enhancing the enzyme activity of PRDX6 in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Li X, Peng SJ, Wang Y, Chen X, Wu TT, Feng Y, Wang XX, Yin H, Wu YC.   +8 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Dissecting a two-domain alginate lyase of family PL6 reveals a mechanistic basis for substrate specificity and enzyme activity. [PDF]

J Biol Chem
Madsen M, Rønne ME, Petersen AB, Tandrup T, Pilgaard B, Holck J, Aachmann FL, Wilkens C, Klau LJ, Svensson B.   +9 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Laboratory warming and wetting drives microbial respiration, enzyme activity, and community composition in a boreal forest soil. [PDF]

FEMS Microbiol Ecol
Gaimaro LW, Doherty SJ, Baker CCM, Aurela M, Barbato RA.   +4 more
europepmc   +1 more source

Synthesis, characterisation, computational study, amelioration of ruthenium kesar nanoparticle, antioxidant and glycolytic enzyme activity alterations in cirrhotic liver extract. [PDF]

Sci Rep
Kanaoujiya R, Dash D, Koiri RK, Mustafa G, Behera K, Srivastava S, Trivedi S, Kumar A, Jaiswal A, Chauhan P, Rawat RK, Singh SP, Diksha, Bartaria D.   +13 more
europepmc   +1 more source

Chrysin ameliorates methotrexate-induced hippocampal neurogenesis impairment by suppressing of oxidative stress and upregulating antioxidant enzyme activity in rodents. [PDF]

PLoS One
Anosri T, Kaewngam S, Prajit R, Suwannakot K, Sritawan N, Aranarochana A, Pannangrong W, Welbat JU, Wigmore P, Sirichoat A.   +9 more
europepmc   +1 more source

Upregulation of angiotensin-(1-7) formation in human podocytes - enzyme activity assay upon fluid flow shear stress. [PDF]

PLoS One
Kaiser-Graf D, Domenig O, Poglitsch M, Kreutz R, Bolbrinker J.   +4 more
europepmc   +1 more source