Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Evaluation of antioxidant enzyme activity among Indian patients with type 2 diabetes mellitus. [PDF]
Singh R +5 more
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
The effects of substituting organic fertilizer for nitrogen fertilizer on seed cotton yield and soil enzyme activity under drip irrigation. [PDF]
Zhou R +6 more
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Effect of Microencapsulated Fermented Catfish Waste Extract on Apparent Metabolizable Energy, Nutrient Digestibility, Digestive Enzyme Activity, and Intestinal Microbiota of Broiler Chickens. [PDF]
Abun A, Haetami K, Ramdhan RF.
europepmc +1 more source
Histological characteristics, hydrolytic enzyme activity, and changes in plant hormones during the seed-shedding process in two Bromus catharticus Vahl. [PDF]
Tian H +5 more
europepmc +1 more source
Amino Acid Variants at the P94 Position in <i>Staphylococcus aureus</i> Class a Sortase Modulate Substrate Binding and Enzyme Activity. [PDF]
Cox-Tigre N +6 more
europepmc +1 more source
Aroma metabolism during the low-temperature storage of Hami melons: volatile odor-active compounds, precursors, and enzyme activity. [PDF]
Hao X +7 more
europepmc +1 more source

