Results 211 to 220 of about 2,214,190 (390)

Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age‐Related Conditions in Mice

Advanced Science, EarlyView.
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang, Qixia Xu, Zhirui Jiang, Rong Sun, Qun Wang, Sanhong Liu, Xin Luan, Judith Campisi, James L. Kirkland, Weidong Zhang, Yu Sun   +10 more
wiley   +1 more source

Immobilization and purification of enzymes with staphylococcal protein A gene fusion vectors.

, 1985
Björn Nilsson, Lars Abrahmsén, Mathias Uhlén   +2 more
openalex   +1 more source

Continuous Hydrolysis of Starch in Membrane Unit Connected Immobilized Enzyme Reactor [PDF]

, 1989
Dudsadee Uttapap, Yojiro Koba, Ayaaki Ishizaki   +2 more
openalex   +1 more source

Lactylation‐Driven NUPR1 Promotes Immunosuppression of Tumor‐Infiltrating Macrophages in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Cai et al. report that tumor‐derived lactate induces NUPR1 expression via H3K18 lactylation, which can promote the pro‐tumor M2 macrophage polarization through ERK and JNK signaling pathways. Treatment with NUPR1 selective inhibitor sensitizes synergizes with anti‐PD‐1 therapy in murine preclinical models.
Jialiang Cai, Peiling Zhang, Yufan Cai, Guiqi Zhu, Shiping Chen, Lina Song, Junxian Du, Biao Wang, Weixing Dai, Jian Zhou, Jia Fan, Yiyi Yu, Zhi Dai   +12 more
wiley   +1 more source

Simple Enzyme Immobilization for Flow Chemistry? An Assessment of Available Strategies for an Acetaldehyde-Dependent Aldolase. [PDF]

Molecules, 2022
Wäscher M, Classen T, Pietruszka J.
europepmc   +1 more source

Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

Advanced Science, EarlyView.
Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li, Liwen Huang, Chenxiao Guo, Jing Ren, Xi Chen, Yachu Ke, Zengyu Xun, Wenzhuo Hu, Yilin Qi, Heping Wang, Zhongying Gong, Xing‐Jie Liang, Xue Xue   +12 more
wiley   +1 more source

A Comprehensive Guide to Enzyme Immobilization: All You Need to Know. [PDF]

Molecules
Robescu MS, Bavaro T.
europepmc   +1 more source

Hyaluronic Acid Allows Enzyme Immobilization for Applications in Biomedicine. [PDF]

Biosensors (Basel), 2022
Arnold J, Chapman J, Arnold M, Dinu CZ.
europepmc   +1 more source

Determination of Glucose, Sucrose, Lactose, and Ethanol in Foods and Beverages, Using Immobilized Enzyme Electrodes

, 1983
Marc Mason
openalex   +1 more source

Vernetzung wäßriger Alginsäure mittels der Vierkomponenten-Kondensation unter Einschluß-Immobilisierung von Enzymen / Crosslinking of Aqueous Alginic Acid by Four Component Condensation with Inclusion Immobilization of Enzymes [PDF]

, 1991
Stephan König, Ivar Ugi
openalex   +1 more source