miR-503 Is Involved in the Protective Effect of Phase II Enzyme Inducer (CPDT) in Diabetic Cardiomyopathy via Nrf2/ARE Signaling Pathway. [PDF]
Biomed Res Int, 2017 Diabetic cardiomyopathy (DCM) is a common heart disease. The Phase II enzyme inducer (CPDT) is a complex enzyme that promotes the expression of antioxidant enzymes through activating nuclear factor erythroid 2-related factor 2 (Nrf2); these compounds ...
Miao Y +8 more
europepmc +2 more sources
ON CATALYTIC REACTIONS INDUCED BY ENZYMES.1 [PDF]
Journal of the American Chemical Society, 1908 n ...
S. F. Acree
openalex +4 more sources
Spironolactone—a weak enzyme inducer in man
Journal of Pharmacy and Pharmacology, 1972 S. A. Taylor, M. Rawlins, S. Smith
semanticscholar +4 more sources
Phoresis and Enhanced Diffusion Compete in Enzyme Chemotaxis [PDF]
Nano Lett. 2018, 18, 4, 2711-2717, 2021 Chemotaxis of enzymes in response to gradients in the concentration of their substrate has been widely reported in recent experiments, but a basic understanding of the process is still lacking. Here, we develop a microscopic theory for chemotaxis, valid for enzymes and other small molecules.
arxiv +1 more source
Reaction-induced molecular dancing and boosted diffusion of enzymes [PDF]
J. Phys. Soc. Jpn. 92, 054801 (2023), 2022 A novel mechanism of reaction-induced active molecular motion, not involving any kind of self-propulsion, is proposed and analyzed. Because of the momentum exchange with the surrounding solvent, conformational transitions in mechano-chemical enzymes are accompanied by motions of their centers of mass.
arxiv +1 more source
From meadows to milk to mucosa – adaptation of Streptococcus and Lactococcus species to their nutritional environments [PDF]
, 2012 Lactic acid bacteria (LAB) are indigenous to food-related habitats as well as associated with the mucosal surfaces of animals. The LAB family Streptococcaceae consists of the genera Lactococcus and Streptococcus.
Kok, Jan, +3 more
core +14 more sources
Halophilic enzyme activation induced by salts [PDF]
Scientific Reports, 2011 Halophilic archea (halobacteriae) thrive in hypersaline environments, avoiding osmotic shock by increasing the ion concentration of their cytoplasm by up to 3-6 M. To remain folded and active, their constitutive proteins have evolved towards a biased amino acid composition.
David Castaño +5 more
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Enzyme-enriched condensates show self-propulsion, positioning, and coexistence [PDF]
, 2023 Enzyme-enriched condensates can organize the spatial distribution of their substrates by catalyzing non-equilibrium reactions. Conversely, an inhomogeneous substrate distribution induces enzyme fluxes through substrate-enzyme interactions. We find that condensates move towards the center of a confining domain when this feedback is weak.
arxiv +1 more source
Cross-diffusion induced patterns for a single-step enzymatic reaction [PDF]
Commun Phys 3, 167 (2020), 2020 Several different enzymes display an apparent diffusion coefficient that increases with the concentration of their substrate. Moreover, their motion becomes directed in substrate gradients. Currently, there are several competing models for these transport dynamics.
arxiv +1 more source
Enhanced diffusion and chemotaxis at the nanoscale [PDF]
Acc. Chem. Res. 2018, 51, 10, 2365-2372, 2021 Enzymes have been recently proposed to have mechanical activity associated with their chemical activity. In a number of recent studies, it has been reported that enzymes undergo enhanced diffusion in the presence of their corresponding substrate, when this substrate is uniformly distributed in solution.
arxiv +1 more source