Results 161 to 170 of about 103,401 (316)

Studies on the mechanism of hormone induction of alkaline phosphatase in human cell cultures, II. Rate of enzyme synthesis and properties of base level and induced enzymes.

, 1966
Martin J. Griffin, R. P. Cox
openalex   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

The electrophilic metabolite of kynurenine, kynurenine-CKA, requires C151 in Keap1 to derepress Nrf2. [PDF]

Redox Biol
Feng J, Carreño M, Jung H, Dayalan Naidu S, Arroyo-Diaz N, Ang AD, Kulkarni B, Kisielewski D, Suzuki T, Yamamoto M, Hayes JD, Honda T, Wilson L, Leon-Ruiz B, Eggler AL, Vitturi DA, Dinkova-Kostova AT.   +16 more
europepmc   +1 more source

Ameliorative Effects of Soya Bean Oil and Vitamin C on Liver Enzymes in Ethanol -Induced Oxidative Stress in Wistar Rats

, 2014
Iosr Journals, Mar Mallo
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

The Use of Metabolic Inducers in Wheat to Increase the Nutritional and Functional Value of Grain. [PDF]

Molecules
Biszczak W, Jośko I, Świeca M, Kraska K, Haliniarz M, Różyło K.   +5 more
europepmc   +1 more source

Inhibitor-induced enzyme activation in organic solvents.

, 1988
Alan J. Russell, Alexander M. Klibanov
openalex   +1 more source

Acute Exercise Induced Mitochondrial H₂O₂Production in Mouse Skeletal Muscle: Association with p^66Shcand FOXO3a Signaling and Antioxidant Enzymes [PDF]

, 2015
Ping Wang, Chun Guang Li, Zhengtang Qi, Di Cui, Shuzhe Ding   +4 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Computational design of allulose-responsive biosensor toolbox for auto-inducible protein expression and CRISPRi mediated dynamic metabolic regulation. [PDF]

Nat Commun
Dong Q, Chen P, Guo Z, Wei H, Zeng Y, Zhang J, Men Y, Liu W, Sun Y, Yang J.   +9 more
europepmc   +1 more source