Effects of α-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on testosterone-induced regeneration of prostate and seminal vesicle in castrated rats [PDF]
Charles Danzin+5 more
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Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei+7 more
wiley +1 more source
The effect of chronic diabetes, induced by streptozotocin, on the activities of some enzymes of glycerolipid synthesis in rat liver [PDF]
P. H. Whiting+5 more
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A rapid and efficient strategy for combinatorial repression of multiple genes in Escherichia coli. [PDF]
Zheng Y, Mo Y, Yuan Y, Su T, Qi Q.
europepmc +1 more source
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee+5 more
wiley +1 more source
Clofibrate-Induced Changes in the Activity of Human Intestinal Enzymes
David Zakim+3 more
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Patterns of induced variation in the morphology, hyaluronic acid secretion, and lysosomal enzyme activity of cultured human synovial cells. [PDF]
J. R. E. Fraser+2 more
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<i>Bacillus subtilis</i> MurJ and Amj Lipid II flippases are not essential for growth. [PDF]
Englehart K, Dworkin J.
europepmc +1 more source
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui+5 more
wiley +1 more source
Enzyme Histochemistry of Induced and Transplanted Squamous Cell Carcinoma of the Uterine Cervix
Michel Thiéry, R. G. J. Willighagen
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