Results 261 to 270 of about 103,401 (316)

Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema

Immunology and Allergy Clinics of North America, 2022
Angioedema is a well-recognized and potentially lethal complication of angiotensin-converting enzyme inhibitor (ACEi) therapy. In ACEi-induced angioedema, bradykinin accumulates due to a decrease in its metabolism by ACE, the enzyme that is primarily responsible for this function.
R Gentry, Wilkerson, Michael E, Winters
openaire   +3 more sources

Angiotensin‐Converting Enzyme Inhibitor‐Induced Cough

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1989
A 65‐year‐old woman started taking enalapril 2.5 mg daily for hypertension. Twelve days later she complained of a persistent, dry cough. Due to the coughing and a preexisting cystocele, she developed stress incontinence and a marked decline in her functional status. The coughing and incontinence resolved with the discontinuation of enalapril.
Hume, Anne L., Murphy, L., Lauerman, Scott E.   +2 more
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Evidence for Lidocaine-Induced Enzyme Inactivation

Journal of Pharmaceutical Sciences, 1989
The effects of lidocaine on hepatic enzyme activity were studied using the isolated perfused rat liver. The in vivo liver activity was examined by infusing lidocaine via the jugular vein, followed by organ isolation and drug perfusion 24 h later. The liver was studied in vitro by perfusing the organ with lidocaine until steady state was reached, then ...
B A, Saville, M R, Gray, Y K, Tam
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[Enzyme-induced masculinization].

Actas urologicas espanolas, 1995
Contribution of two cases of congenital adrenal hyperplasia by blockade in the 21-hydroxylase enzyme synthesis. Diagnosis was reached from the clinical signs and symptoms (virilization syndrome), and was confirmed by radiological and laboratory tests.
F F, Chagas, D, Pesqueira, C, Ferreira, H, Jorge, R, Monnerat, F, Meijide, M, Pereiro, E, Zungri   +7 more
openaire   +1 more source

Exercise stress and enzyme-induced emphysema

Journal of Applied Physiology, 1976
Rats were exposed to an aerosol of 10% papain for 8 h found in pilot studies to produce marked emphysema. One week after exposure some animals were forced to exercise in a motor-driven activity wheel 2 h daily for 4 wk, while others remained at rest. Another group of rats which served as the control were exposed to saline under the same conditions and
H, Sahebjami, C L, Vassallo
openaire   +2 more sources

Angiotensin-converting Enzyme Inhibitor-induced Angioedema

The American Journal of Medicine, 2015
Angiotensin-converting enzyme inhibitors (ACE-I) are widely used, effective, and well-tolerated antihypertensive agents. The mechanisms by which those agents act can cause side effects such as decreased blood pressure, hyperkalemia, and impaired renal function. ACE-I can induce cough in 5%-35% and angioedema in up to 0.7% of treated patients.
Shira, Bezalel, Keren, Mahlab-Guri, Ilan, Asher, Ben, Werner, Zev Moshe, Sthoeger   +4 more
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Ozone-induced inactivation of antioxidant enzymes

Biochimie, 2003
Ozone is an air pollutant that damages a variety of biomolecules. We investigated ozone-induced inactivation of three major antioxidant enzymes. Cu/Zn superoxide dismutase was inactivated by ozone in a concentration-dependent manner. The concentration of ozone for 50% inactivation was approximately 45 microM when 10 microM Cu/Zn superoxide dismutase ...
Yong-Ki, Lee, Sang, Mok Kim, Sanghwa, Han   +2 more
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The Angiotensin-Converting-Enzyme-Induced Angioedema

Immunology and Allergy Clinics of North America, 2017
The bradykinin B2 receptor antagonist icatibant is effective in angiotensin-converting enzyme inhibitor-induced angioedema. The drug is not approved officially for this indication and has to be administered in an emergency situation off-label. Corticosteroids or antihistamines do not seem to work in this condition.
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