Results 81 to 90 of about 103,401 (316)

Isolation, Production Optimization, and Purification of a Debittering Enzyme from Bacillus megaterium AULS 1 [PDF]

Chemical and Biochemical Engineering Quarterly
Bitterness in citrus juice is a common quality issue in the fruit-based beverage industry. Naringin, the dominant flavonoid responsible for bitterness in citrus fruit juice, can be mitigated by the enzyme naringinase.
G. N. Devi, G. Sangavi, M. Chakravarthy , J. L. Sweetlin   +3 more
doaj   +1 more source

Effect of Catha edulis on the Activities of Enzyme Markers of Carcinogenicity in Chemically-induced Hepatocellular Carcinoma in Rabbits [PDF]

, 2014
Haider Al-Mamary, Amina El-Shaiban, Molham Al‐Habori, Ali Al‐Meeri, Adel S. Al-Zubairi, Mohamed Al-Mamary   +5 more
openalex   +1 more source

Amelioration of heat stress-induced hepatic injury in wistar rats by zinc-enriched probiotics: Role of hepatic antioxidant status and serum enzymes activity

, 2021
Rahmani Mohammad Malyar
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Optimized Condition for Enhanced Soluble-Expression of Recombinant Mutant Anabaena Variabilis Phenylalanine Ammonia Lyase

Advanced Pharmaceutical Bulletin, 2014
Purpose: Recently discovered Anabaena variabilis phenylalanine ammonia lyase (AvPAL) proved to be a good candidate for enzyme replacement therapy of phenylketonuria. Outstanding stability properties of a mutant version of this enzyme, produced already in
Hossein Zarei Jaliani, Safar Farajnia, Yaghoub Safdari, Seyyed Abolghasem Mohammadi, Abolfazl Barzegar, Saeed Talebi   +5 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

STREPTOMYCES FRADIAE, A POTENT PRODUCER OF CHOLESTEROL OXIDASE [PDF]

Journal of Sciences, Islamic Republic of Iran, 1999
Thirteen species of Streptomycetes, Arthrobacters and Mycobacterium were studied for the determination of a potential cholesterol oxidase producer. Only Streptomyces fradiae and Streptomyces rishiriences were found to be capable of producing this enzyme.
doaj  

Enzymes That Scavenge Reactive Oxygen Species Are Down-Regulated Prior to Gibberellic Acid-Induced Programmed Cell Death in Barley Aleurone [PDF]

, 2001
Angelika Fath, Paul C. Bethke, Russell L. Jones   +2 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Suppression of spontaneous and hydrogen peroxide‐induced mutations by a MutT‐type nucleotide pool sanitization enzyme, the Escherichia coli Orf135 protein [PDF]

, 2003
Hiroyuki Kamiya, Emiko Iida, Naoko Murata‐Kamiya, Yoshihiro Yamamoto, Takeyoshi Miki, Hideyoshi Harashima   +5 more
openalex   +1 more source