Results 151 to 160 of about 415,303 (195)

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

Advanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou, Lauren Brown, Christopher M. Madl   +2 more
wiley   +1 more source

Engineered Peptides‐Based Hybrid‐Nested Microneedle Effectively Treat Biofilm‐Infected Diabetic Wounds

Advanced Functional Materials, EarlyView.
A hybrid‐nested microneedle/cryogel scaffold (MQW‐CMg‐MOF) is designed for efficient biofilm removal and accelerated healing of diabetic wounds. The scaffold shows substantial biofilm removal in vitro and in a preclinical diabetic swine biofilm‐infected wound model compared to the control.
Syed Muntazir Andrabi, S. M. Shatil Shahriar, Yiran Tian, Farzad Hayati, Yajuan Su, Feng Zhang, Navatha Shree Sharma, Guangshun Wang, Shannon L. Wong, Zheng Yan, Guoliang Huang, Jingwei Xie   +11 more
wiley   +1 more source

Multifunctional Hydroxyapatite Coated with Gallium Liquid Metal‐Based Silver Nanoparticles for Infection Prevention and Bone Regeneration

Advanced Functional Materials, EarlyView.
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen, Pengfei Zhang, Fathima Shana Pattar Kadavan, Zhaoning Xu, Tien Thanh Nguyen, Wenshao Li, Manh Tuong Nguyen, Chung Kim Nguyen, Duy Quang Pham, Thi Giang Tuyet Pham, Andrew Hayles, Markos Negash Alemie, Jitraporn Vongsvivut, Vincent Chan, Stephen Peter Kidd, Yunpeng Zhao, Krasimir Vasilev, Vi Khanh Truong   +17 more
wiley   +1 more source

Cell Membrane Vesicle Camouflaged Artificial Cells

Advanced Functional Materials, EarlyView.
Artificial cells camouflaged with a cell membrane vesicle coating are able to assemble into synthetic aggregates that exhibit rudimentary communication capabilities. Additionally, when these artificial cells are equipped with antioxidant capabilities, they are able to protect the intracellular homeostasis in HepG2 cells present in semi‐synthetic ...
Paula De Dios Andres, Stefan Pendlmayr, Noga Gal, Cathrine Abild Meyer, Cecilie Ryberg, Olav Vestrheim, Noel Angelo Kalacas, Fatih Demir, Markus M. Rinschen, Karsten Haupt, Rajeshwar Prosad Mookerjee, Brigitte Städler   +11 more
wiley   +1 more source

Hepatic Enzyme Induction [PDF]

Toxicologic Pathology, 2010
Hepatic enzyme induction is generally an adaptive response associated with increases in liver weight, induction of gene expression, and morphological changes in hepatocytes. The additive growth and functional demands that initiated the response to hepatic enzyme induction cover a wide range of stimuli including pregnancy and lactation, hormonal ...
Robert R. Maronpot, Gundi Mueller, Takanori Harada, Jerrold M. Ward, Bhanu Singh, Katsuhiko Yoshizawa, Abraham Nyska, Gordon P. Flake   +7 more
openaire   +2 more sources

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Enzyme induction and inhibition

Pharmacology & Therapeutics, 1990
The rate and extent of drug metabolism significantly influences drug effect. Enzyme induction by increasing the metabolism of drugs may result in important drug interactions. Other implications of enzyme induction include alterations in the metabolism of endogenous substrates, vitamins and activity of extrahepatic enzyme systems. Similarly a wide range
M. Barry, J. Feely
openaire   +3 more sources

ENZYME INDUCTION BY ESTROGEN

Journal of Steroid Biochemistry, 1983
The injection of estrogen into an immature or ovariectomized rat results in an increase in the specific activities of many uterine enzymes which can be detected, usually, within hours to days. The recent identification of the "estrogen-induced protein" as the brain type isozyme of creatine kinase (CKBB), provided an easily measurable enzyme marker, the
openaire   +3 more sources

Enzyme Induction by Coumarins

Drug Development and Industrial Pharmacy, 1977
The sodium pentobarbital sleeping time in mice was studied after pretreatment with coumarins (coumarin, 4-hydroxycoumarin, 7-hydroxycoumarin, acenocoumarol, bis-hydroxycoumarin, phenprocoumon and w...
Wolfgang A. Ritschel, Li Hwa Lee
openaire   +2 more sources

Enzyme induction by oral testosterone

Clinical Pharmacology & Therapeutics, 1976
Six normal male volunteers ingested a dose of 400 mg free testosterone daily as tablets over 21 days. By the end of treatment intravenous antipyrine half‐life had decreased significantly from 8.0 ± 2.7 to 5.7 ± 2.6 hr. The subjects eliminated testosterone from serum more rapidly on the twenty‐first day of testosterone ingestion than on the first day ...
Edgar P. Bennett, Jens P. Kampmann, F. Schønau Jørgensen, Svend G. Johnsen   +3 more
openaire   +2 more sources

Enzyme induction in catabolic systems [PDF]

, 2004
Enzymatic adaptation, as it had been studied by Karstrom can be defined as the induced appearance of specific enzymes after a preliminary “adaptation” of microorganisms on their substrates. The term of enzymatic adaptation has been replaced by enzyme induction.
openaire   +1 more source