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High-level production of vitamin K2 in <i>Escherichia coli</i> via modular molecular engineering. [PDF]

Synth Syst Biotechnol
Lu Z, Huang Z, Wu Z, Zhu Z, Zhu Y, Teng X, Chen H, Zhou J, Ma F, Wang X.   +9 more
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Hepatic Enzyme Induction

Toxicologic Pathology, 2010
Hepatic enzyme induction is generally an adaptive response associated with increases in liver weight, induction of gene expression, and morphological changes in hepatocytes. The additive growth and functional demands that initiated the response to hepatic enzyme induction cover a wide range of stimuli including pregnancy and lactation, hormonal ...
Robert R, Maronpot, Katsuhiko, Yoshizawa, Abraham, Nyska, Takanori, Harada, Gordon, Flake, Gundi, Mueller, Bhanu, Singh, Jerrold M, Ward   +7 more
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ENZYME INDUCTION BY ESTROGEN

Journal of Steroid Biochemistry, 1983
The injection of estrogen into an immature or ovariectomized rat results in an increase in the specific activities of many uterine enzymes which can be detected, usually, within hours to days. The recent identification of the "estrogen-induced protein" as the brain type isozyme of creatine kinase (CKBB), provided an easily measurable enzyme marker, the
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Trans-synaptic enzyme induction

Life Sciences, 1974
Publisher Summary This chapter discusses the trans-synaptic enzyme induction. The increase in tyrosine hydroxylase synthesis is not a manifestation of a general increase in protein synthesis in the adrenergic neuron because under experimental conditions leading to a 2- to 3-fold increase in tyrosine hydroxylase activity, there was no detectable ...
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Dose‐dependent enzyme induction

Clinical Pharmacology & Therapeutics, 1973
Administration of qUinalbarbitone, 100 mg nightly, caused a fall in steady‐state plasma warfarin concentration ranging from 5% to 64.5% in 6 patients. There was no correlation between the extent of this fall and either the plasma concentration of quinalbarbitone or the initial rate of warfarin metabolism.
A, Breckenridge, M L, Orme, L, Davies, S S, Thorgeirsson, D S, Davies   +4 more
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Enzyme induction and inhibition

Pharmacology & Therapeutics, 1990
The rate and extent of drug metabolism significantly influences drug effect. Enzyme induction by increasing the metabolism of drugs may result in important drug interactions. Other implications of enzyme induction include alterations in the metabolism of endogenous substrates, vitamins and activity of extrahepatic enzyme systems. Similarly a wide range
M, Barry, J, Feely
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Enzyme induction by oral testosterone

Clinical Pharmacology & Therapeutics, 1976
Six normal male volunteers ingested a dose of 400 mg free testosterone daily as tablets over 21 days. By the end of treatment intravenous antipyrine half‐life had decreased significantly from 8.0 ± 2.7 to 5.7 ± 2.6 hr. The subjects eliminated testosterone from serum more rapidly on the twenty‐first day of testosterone ingestion than on the first day ...
S G, Johnson, J P, Kampmann, E P, Bennett, F S, Jorgensen   +3 more
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Enzyme patterns during bone induction

Calcified Tissue Research, 1970
The results are as yet preliminary. The tendency for quantitative variation is given in Fig. 1 and the relative variation in isoenzyme pattern of LDH in Fig. 2. LDH activity increased parallel with increased level of metabolism and had a marked activity located to osteoblasts when new bone formation started.
K, Buring, H, Semb
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