Results 141 to 150 of about 689,457 (314)

Mechanism of action of penicillin: triggering of the pneumococcal autolytic enzyme by inhibitors of cell wall synthesis. [PDF]

, 1975
Alexander Tomasz, Susan Waks
openalex   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blockers, and the Risk of Acute Pancreatitis: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Alves C, Costa B, Penedones A, Mendes D, Batel Marques F.   +4 more
europepmc   +1 more source

EFFECTS OF ENZYME INHIBITORS ON JUNCTION POTENTIALS IN RESPONSE TO ADRENERGIC NERVE STIMULATION

, 1969
Hironori Nakanishi, Masami Doteuchi, Koichi Otani, Hideo Tanaka, Hiroshi Takeda   +4 more
openalex   +1 more source

alpha-N-Benzoylarginine-2-naphthylamide Hydrolase (Cathepsin B1 ?) from Rat Skin. II. Purification of the Enzyme and Demonstration of Two Inhibitors in the Skin. [PDF]

, 1975
M. Järvinen, V. K. Hopsu‐Havu, Mona Grönlund, Anna‐Britta Hörnfeldt, Rolf Servin, Hans Sternerup   +5 more
openalex   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

Synthesis, Biological Evaluation, and In Silico Characterization of Novel Imidazothiadiazole-Chalcone Hybrids as Multi-Target Enzyme Inhibitors. [PDF]

Pharmaceuticals (Basel)
Alici H, Topuz S, Demir K, Taslimi P, Tahtaci H.   +4 more
europepmc   +1 more source

A Structural and In Silico Investigation of Potential CDC7 Kinase Enzyme Inhibitors. [PDF]

ACS Omega, 2023
Mookkan M, Kandasamy S, Al-Odayni AB, Abduh NAY, Srinivasan S, Revannasidappa BC, Kumar V, Chinnasamy K, Aravindhan S, Shankar MK.   +9 more
europepmc   +1 more source

Effects of Some Enzyme Inhibitors Added to the Inoculum in Mechanical Inoculation of Soil-Borne Viruses of Wheat and Barley

, 1967
K. Takanashi, Yasuo Saito, Yoshito Iwata
openalex   +2 more sources

Characterization of a proteolytic-enzyme inhibitor with allergenic activity. Multiple functions of a parasite-derived protein [PDF]

, 1979
Peter Willadsen, George Riding
openalex   +1 more source