Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
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EFFECTS OF ENZYME INHIBITORS ON JUNCTION POTENTIALS IN RESPONSE TO ADRENERGIC NERVE STIMULATION
Hironori Nakanishi+4 more
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A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors [PDF]
Peter J. F. Henderson
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The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
Orally active angiotensin‐converting enzyme inhibitor (SO 14,225) as a treatment for essential hypertension. [PDF]
Brunner Hr+6 more
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Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
Effect of Glycidate, an Inhibitor of Glycolate Synthesis in Leaves, on the Activity of Some Enzymes of the Glycolate Pathway [PDF]
Israel Zelitch
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Changes in levels of enzyme inhibitors during soaking and cooking for pulses available in Canada
Lan Shi+3 more
semanticscholar +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns+2 more
wiley +1 more source