Results 161 to 170 of about 700,443 (307)

Enzyme Inhibitor [PDF]

, 2020
openaire   +1 more source

The Profibrinolytic Enzyme Subtilisin NAT Purified fromBacillus subtilis Cleaves and Inactivates Plasminogen Activator Inhibitor Type 1 [PDF]

, 2001
Tetsumei Urano, Hayato Ihara, Kazuo Umemura, Yasuhiro Suzuki, Masaki Oike, Sumio Akita, Yoshinori Tsukamoto, Isao Suzuki, Akikazu Takada   +8 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Exploring the Potential of Pyridine Carboxylic Acid Isomers to Discover New Enzyme Inhibitors. [PDF]

Drug Des Devel Ther
Yaqoob S, Khan FA, Tanveer N, Ali S, Hameed A, El-Seedi H, Jiang ZH, Wang Y.   +7 more
europepmc   +1 more source

Influence of Type of Questionnaire on the Prevalence of Coughing in Patients Taking Angiotensin Converting Enzyme Inhibitors(ACEI).

, 1996
Nobuyuki Goto, Masaki Shirahase, Hisao HATTA, Mikio Masada, Jong‐Dae Lee, Akiyoshi Tsubokawa, Hiromasa Shimizu, Takanori Ueda, Tõru Nakamura, SHIKIFUMI KITAZAWA   +9 more
openalex   +2 more sources

Efficacy of p-hydroxy-phenyl-pyruvate dioxygenase (HPPD) enzyme-inhibitive tembotrione and topramezone herbicides for weed-management in rainy season grain sorghum (Sorghum bicolor)

, 2023
Arvind Verma, B. Gangaiah, Vilas A. Tonapi   +2 more
openalex   +2 more sources

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Angiotensin-converting enzyme inhibitors for aortic stenosis: a drug-target Mendelian randomization study. [PDF]

Int J Cardiol Heart Vasc
Ciofani JL, Han D, Woolf B, Gill D, Allahwala UK, Bhindi R.   +5 more
europepmc   +1 more source

Investigation of Effective Natural Inhibitors for Starch Hydrolysing Enzymes from Simaroubaceae Plants by Molecular Docking Analysis and Comparison with In-Vitro Studies

, 2021
Kirana P. Mugaranja, K. Ananda
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source