Results 251 to 260 of about 700,443 (307)

Comparative Efficacy and Safety of Angiotensin-Converting Enzyme Inhibitors, Angiotensin Receptor Blockers, and Calcium Channel Blockers in Hypertensive Patients With Chronic Kidney Disease: A Systematic Review. [PDF]

Cureus
Mhmndar MA, Singh T, Fatima I, Shehryar A, Zaidi MR, Mairaj M, Khan SM, Kolanu ND, Ahmed S, Kamal A, Rehman A, Quinn M.   +11 more
europepmc   +1 more source

Response to allopurinol and febuxostat according to the fractional excretion of urate in men with gout

Arthritis Care &Research, Accepted Article.
Background Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of urate (FEUA) also modulates this response and relates to oxypurinol concentrations. We further evaluated its potential influence
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers Is Associated With a Reduced Risk of Poststroke Epilepsy in Patients With Ischemic Stroke. [PDF]

J Am Heart Assoc
Chang KC, Lin CH, Huang JA.
europepmc   +1 more source

Preoperative continuation vs. discontinuation of angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers on early cognitive function in elderly patients undergoing noncardiac surgery: a randomized controlled trial. [PDF]

Front Aging Neurosci
Wang X, Yan Y, Liu Y, Xu C, Zhuang J, Wang Z.   +5 more
europepmc   +1 more source

A Meta-Analysis of the Impact of Using Angiotensin-Converting Enzyme Inhibitors (ACEIs) or Angiotensin II Receptor Blockers (ARBs) on Mortality, Severity, and Healthcare Resource Utilization in Patients with COVID-19. [PDF]

Adv Respir Med
Li R, Zhang J, Ren L.
europepmc   +1 more source

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Inhibitors of glyoxalase enzymes

Biochemical and Biophysical Research Communications, 1980
Abstract Both glyoxalase enzymes from various sources are inhibited by nucleotides, nucleosides and a series of structurally related compounds in an apparently cooperative manner. In general, aromatic compounds, which contain heterocyclic nitrogen and/or have amino groups on the aromatic ring, are effective inhibitors of these enzymes.
B, Oray, S J, Norton
openaire   +2 more sources

Pyranoid Spirosugars as Enzyme Inhibitors

Current Organic Synthesis, 2021
Background: Pyranoid spirofused sugar derivatives represent a class of compounds with a significant impact in the literature. From the structural point of view, the rigidity inferred by the spirofused entity has made these compounds object of interest mainly as enzymatic inhibitors, in particular, carbohydrate processing enzymes.
La Ferla, Barbara, D'Orazio, Giuseppe
openaire   +3 more sources

Enzyme kinetics in relation to enzyme inhibitors

Biochemical Pharmacology, 1973
Abstract A Large number of pharmacologically important compounds have been found to act as enzyme inhibitors and a kinetic study of the inhibitory process can provide important information on the potency of the compound and on its mode of interaction with the enzyme.
openaire   +2 more sources