Results 321 to 330 of about 5,633,974 (393)
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Angewandte Chemie, 2021
Molecular imprinting represents one of the most promising strategies to design artificial enzyme inhibitors. However, the study of molecularly imprinted enzyme inhibitors (MIEIs) remains at a primary stage.
Jingjing Xu +5 more
semanticscholar +1 more source
Molecular imprinting represents one of the most promising strategies to design artificial enzyme inhibitors. However, the study of molecularly imprinted enzyme inhibitors (MIEIs) remains at a primary stage.
Jingjing Xu +5 more
semanticscholar +1 more source
Journal of the American Medical Association (JAMA), 2020
Coronavirus disease 2019 (COVID-19) is a current pandemic infection caused by a positive-sense RNA virus named the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The particularly infectious capacity of the virus, along with mortality rates
Ankit B. Patel, A. Verma
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Coronavirus disease 2019 (COVID-19) is a current pandemic infection caused by a positive-sense RNA virus named the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The particularly infectious capacity of the virus, along with mortality rates
Ankit B. Patel, A. Verma
semanticscholar +1 more source
Letters in Drug Design & Discovery, 2020
Phenolic Mannich bases have been reported as acetylcholinesterase (AChE) inhibitors for the medication of Alzheimer's disease. Carbonic Anhydrases (CAs) are molecular targets for anticonvulsant, diuretic and antiglaucoma drugs in the clinic.
C. Yamali +4 more
semanticscholar +1 more source
Phenolic Mannich bases have been reported as acetylcholinesterase (AChE) inhibitors for the medication of Alzheimer's disease. Carbonic Anhydrases (CAs) are molecular targets for anticonvulsant, diuretic and antiglaucoma drugs in the clinic.
C. Yamali +4 more
semanticscholar +1 more source
Advances in Discovering Deubiquitinating Enzyme (DUB) Inhibitors.
Journal of Medicinal Chemistry, 2020Deubiquitinating enzymes, or DUBs, comprise a family of proteases that regulate ubiquitination dynamics. Since their discovery in the 1980s, genetic and functional studies have nominated DUBs as a promising class for drug discovery across diverse ...
N. Schauer +4 more
semanticscholar +1 more source
[Angiotensin-converting enzyme inhibitors].
Recenti progressi in medicina, 1991The introduction of angiotensin-converting enzyme (ACE) inhibitors for the treatment of hypertension and heart failure is probably the most important advance in cardiovascular pharmacotherapy in the last few decades. Although the role of the renin-angiotensin system (RAS) in cardiovascular diseases had been investigated extensively for more than 70 yr,
Irene Gavras, Haralambos Gavras
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Angiotensin-converting enzyme inhibitors
Critical Care Nurse, 1990This review focuses on the use of angiotensin converting enzyme (ACE) inhibitors in hypertensive diseases. Specifically discussed are: proposed mechanisms of action, the pharmacology of the commercially available ACE inhibitors (captopril, enalapril, and lisinopril), their renal effects, and their safety and efficacy.
B L, Herlihy, J T, Herlihy
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Inhibitors of glyoxalase enzymes
Biochemical and Biophysical Research Communications, 1980Abstract Both glyoxalase enzymes from various sources are inhibited by nucleotides, nucleosides and a series of structurally related compounds in an apparently cooperative manner. In general, aromatic compounds, which contain heterocyclic nitrogen and/or have amino groups on the aromatic ring, are effective inhibitors of these enzymes.
B, Oray, S J, Norton
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Angiotensin-converting enzyme inhibitors
2001Publisher Summary Angiotensin-converting enzyme (ACE) inhibitors were first studied clinically in the 1970s. ACE inhibitors were discovered by taking advantage of previous basic research on the physiology of sodium, potassium, and water homeostasis and blood pressure regulation, in a reciprocal way ACE have also advanced research in this field, and ...
J, Menard, A A, Patchett
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